59362-73-1

Upstream product

• 825-40-1 2-bromo-p-chloroacetophenone 
• 32345-65-6 (DL)-o-chlorophenyl-1,2-ethanediol 
• 536-38-9 4-chlorobenzoylmethyl bromide 

Downstream Products

• 59363-25-6 1-[4-(2-chloro-phenyl)-2-(4-chloro-phenyl)-[1,3]dioxolan-2-ylmethyl]-1H-imidazole 

Relevant academic research and scientific papers

Antimycotic Imidazoles. 5. Synthesis and Antimycotic Properties of 1-methyl>-1H-imidazoles

The synthesis of 1-methyl>-1H-imidazoles is described starting with phenylacetyl bromides or 1-(phenylacetyl)imidazoles.The compounds were generally obtained as cis/trans mixtures and found to be active in vitro against dermatophytes, yeasts, other fungi, and Gram-positive bacteria.Some also showed good activity against Candida albicans in vivo.

2-Aryl-2-halomethyl-4-alkenyl-1,3-dioxolanes

Novel compounds denoted as 2-aryl-2-halomethyl-4-alkenyl-1,3-dioxolanes used as intermediates in making 1-(2-Ar-4-R-1,3-dioxolan-2-ylmethyl)imidazoles, useful as antifungal and antibacterial agents.

1,3-Dioxolan-2-ylmethylimidazoles

Novel 1-(2-Ar1 -4-Ar2 -1,3-dioxolan-2-ylmethyl)imidazoles, 1-[2-Ar1 -4-(Ar2 -oxymethyl)-1,3-dioxolan-2-ylmethyl]imidazoles, 1-[2-Ar1 -4-(Ar2 -thiomethyl)-1,3-dioxolan-2-ylmethyl]imidazoles,