59415-76-8Relevant academic research and scientific papers
Stereo- and Regioselective Palladium-Catalyzed 1,4-Dialkoxylation of Conjugated Dienes
Baeckvall, Jan-E.,Vaegberg, Jan O.
, p. 5695 - 5699 (2007/10/02)
A mild method for stereo- and regioselective 1,4-dialkoxylation of conjugated dienes was developed.The reaction is catalysed by palladium(II), and p-benzoquinone is used as the oxidant.It was found that the reaction rate depended on the presence of catalytic amounts of a strong acid.The role of the acid is probably 2-fold: (i) to create a cationic (?-allyl)palladium intermediate and (ii) to protonate the oxygen in the coordinated benzoquinone in the (?-allyl)palladium(benzoquinone) intermediate.
STEREOCHEMISTRY OF ALLYLIC CARBON-OXYGEN AND CARBON-CARBON BOND FORMATION IN PALLADIUM-CATALYZED DECARBOXYLATION OF ALLYLIC CARBONATES AND ACETOACETATES
Baeckvall, Jan-E.,Nordberg, Ruth E.,Vagberg, Jan
, p. 411 - 412 (2007/10/02)
Palladium-catalyzed decarboxylation of allylic carbonates(cis- and trans-4) and allylic acetoacetates (cis- and trans-5) results in carbon-oxygen and carbon-carbon bond formation with both retention and inversion of configuration at the allylic position.T
