59447-12-0

Usage

Uses

Used in Pharmaceutical Industry:
3-OXO-3-(4-PHENOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER is used as an anti-inflammatory agent for its ability to inhibit the production of prostaglandins, which are responsible for inflammation, pain, and fever in the body.
Used in Treatment of Rheumatoid Arthritis:
3-OXO-3-(4-PHENOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER is used as a therapeutic agent for managing the symptoms of rheumatoid arthritis, including pain, swelling, and stiffness.
Used in Treatment of Osteoarthritis:
3-OXO-3-(4-PHENOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER is used as a pain reliever and anti-inflammatory drug for the treatment of osteoarthritis, helping to alleviate joint pain and improve mobility.
Used in Management of Musculoskeletal Pain:
3-OXO-3-(4-PHENOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER is used as an analgesic for the management of musculoskeletal pain, providing relief from discomfort and promoting healing.
Used in Pharmaceutical Formulations:
3-OXO-3-(4-PHENOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER is used as an active pharmaceutical ingredient to improve the solubility and bioavailability of the drug, enhancing its effectiveness in treating pain and inflammation.

InChI:InChI=1/C17H16O4/c1-2-20-17(19)12-16(18)13-8-10-15(11-9-13)21-14-6-4-3-5-7-14/h3-11H,2,12H2,1H3

Upstream product

• 64-17-5 ethanol 
• 56944-73-1 2,2-bis(methylthio)vinyl 4-phenoxyphenyl ketone 
• 40501-36-8 2-phenoxybenzoyl chloride 
• 6148-64-7 ethyl potassium malonate 
• 5031-78-7 4-phenoxyacetophenone 
• 105-58-8 Diethyl carbonate 

Downstream Products

• 1558038-27-9 C₁₇H₁₅ClO₄ 
• 1558038-28-0 C₃₀H₃₄N₂O₅S 
• 1558038-29-1 C₂₃H₂₃N₃O₂S 
• 1558038-33-7 C₂₉H₃₂N₂O₅S 
• 1558036-89-7 C₂₆H₂₃N₃O₃S 
• 1558037-10-7 C₂₆H₂₅N₃O₃S 
• 105769-21-9 ethyl 2-acetylthio-2-(4-phenoxybenzoyl)acetate 

Relevant academic research and scientific papers

PARAZOLE CONDENSED-RING DERIVATIVES AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN TREATMENT OF CANCERS, INFLAMMATION AND IMMUNE DISEASES

The present invention relates to pyrazole fused-ring derivatives, their preparation methods, and use thereof in medicine. In particular, the present invention relates to a novel derivative represented by formula (I), and a pharmaceutically acceptable salt

Aromatic amide derivative, preparation method therefor and application of aromatic amide derivative in medicines

The invention relates to an aromatic amide derivative, a preparation method therefor and application of the aromatic amide derivative in medicines. Specifically, the invention relates to a novel derivative represented by a general formula (I) shown in the description and pharmaceutical salts thereof or pharmaceutical compositions containing the novel derivative, and preparation methods thereof. The invention further relates to use of the derivative and the pharmaceutical salts thereof or pharmaceutical compositions containing the derivative in preparation of therapeutic agents, particularly Bruton tyrosine kinase inhibitors, and in preparation of medicines for treating and/or preventing diseases such as tumor and immunity related diseases. Each substituent of the general formula (I) is the same as defined in the description.

SUBSTITUTED NICOTINIMIDE INHIBITORS OF BTK AND THEIR PREPARATION AND USE IN THE TREATMENT OF CANCER, INFLAMMATION AND AUTOIMMUNE DISEASE

Compounds of Formula I, as shown below and defined herein: and pharmaceutically acceptable salts, syntheses, intermediates, formulations, and methods of treating diseases including cancer, inflammation, and autoimmune disease mediated at least in part by Bruton's Tyrosine Kinase (BTK).

HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS

The present invention encompasses compounds of the formula (I) wherein the groups A, Cy, X1 and Y are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.

HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS

The present invention encompasses compounds of the formula (I) wherein the groups ring A and Cy are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.

THIAZOLES, IMIDAZOLES, AND PYRAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES

The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and the compositions in the treatment of

THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP

A compound of formula (I) in which R is lower alkyl, halogen, optionally substituted heterocyclic group or optionally substituted aryl, R is carboxy, protected carboxy or amidated carboxy, Ar is optionally substituted aryl or optionally substituted heterocyclic group, A is lower alkylene, X is oxa or a single bond, Y is thia, sulfinyl or sulfonyl, Z is methylene, thia, sulfinyl or sulfonyl, m and n are each an integer of 0 to 6, and 1/=m+n/=6, or its salt, which is useful as an inhibitor of matrix metalloproteinases (MMP) or tumor necrosis factor alpha (TNF alpha ).