59467-67-3Relevant articles and documents
PROCESS FOR PRODUCING HIGHLY PURE MIDAZOLAM AND SALTS THEREOF
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Page/Page column 5-6, (2009/04/24)
Provided is a process for producing highly pure midazolam and salts thereof, and a pharmaceutical composition containing the highly pure midazolam and/or a salt thereof.
1,2,5-Oxadiazino[5,4-a][1,4]benzodiazepine derivatives
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, (2008/06/13)
A multistep process is presented for the preparation of imidazobenzodiazepines of the formula STR1 wherein X is selected from the group consisting of hydrogen, halogen, nitro and trifluoromethyl, Y is selected from the group consisting of hydrogen, halogen and trifluoromethyl and R1 is selected from the group consisting of hydrogen, lower alkyl and aryl Also presented are novel intermediates utilized in the process. The end products are useful as sedatives, anxiolytics, muscle relaxants and anticonvulsants. The end products are especially useful in intravenous compositions for use in preoperative anesthesia.