594836-40-5

Upstream product

• 931-51-1 cyclohexylmagnesiumchloride 
• 446021-62-1 (2S,3aR,8aS)-3-(mesitylsulfonyl)-3,3a,8,8a-tetrahydroindeno[1,2-d][1,2,3]oxathiazole-2-oxide 
• 175848-32-5 N-((1R,2S)-2-Hydroxy-indan-1-yl)-2,4,6-trimethyl-benzenesulfonamide 
• 861821-86-5 2-Methyl-propane-2-sulfinic acid (1R,2S)-1-(2,4,6-trimethyl-benzenesulfonylamino)-indan-2-yl ester 
• 446021-63-2 (2S,3aR,8aS)-3-(2,4,6-Trimethyl-benzenesulfonyl)-3,3a,8,8a-tetrahydro-1-oxa-2-thia-3-aza-cyclopenta[a]indene 2-oxide 

Downstream Products

• 446021-63-2 (2S,3aR,8aS)-3-(2,4,6-Trimethyl-benzenesulfonyl)-3,3a,8,8a-tetrahydro-1-oxa-2-thia-3-aza-cyclopenta[a]indene 2-oxide 
• 175848-32-5 N-((1R,2S)-2-Hydroxy-indan-1-yl)-2,4,6-trimethyl-benzenesulfonamide 

Relevant academic research and scientific papers

A highly selective and practical method for enantiopure sulfoxides utilizing activated and functionally differentiated N-sulfonyl-1,2,3-oxathiazolidine-2-oxide derivatives

New, stereoselective, and general methods for the preparation enantiopure sulfoxides by using norephedrine tosylate as a chiral auxiliary are described. The product may be obtained either stepwise, or in a one-pot reaction (see scheme). Furthermore, the c

Practical and highly stereoselective technology for preparation of enantiopure sulfoxides and sulfinamides utilizing activated and functionally differentiated N-sulfonyl-1,2,3-oxathiazolidine-2-oxide derivatives

A simple, general, and practical technology to prepare enantiopure 1,2,3-oxathiazolidine-2-oxide derivatives using chiral aryl N-sulfonyl aminoalcohol derivatives and thionyl chloride is reported. The versatility of these novel chiral building blocks (MIOO and TMPOO), was exemplified by the expedient production of a variety of unique chiral sulfoxides and valuable chiral sulfinamides in excellent yields and enantiopurities.