594844-72-1

Basic information

• Product Name: Methyl 2-(4-amino-3-(dimethylcarbamoyl)phenyl)acetate
• Synonyms: Methyl 2-(4-amino-3-(dimethylcarbamoyl)phenyl)acetate
• CAS NO: 594844-72-1
• Molecular Formula: C₁₂H₁₆N₂O₃
• Molecular Weight: 236.26704
• Mol File: 594844-72-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl 2-(4-amino-3-(dimethylcarbamoyl)phenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-(4-amino-3-(dimethylcarbamoyl)phenyl)acetate(594844-72-1)
• EPA Substance Registry System: Methyl 2-(4-amino-3-(dimethylcarbamoyl)phenyl)acetate(594844-72-1)

Safety Data

• Hazardous Substances Data: 594844-72-1(Hazardous Substances Data)

Upstream product

• 1350468-85-7 [3-(dimethylcarbamoyl)-4-nitrophenyl]acetic acid 
• 1350468-86-8 dimethyl [3-(dimethylcarbamoyl)-4-nitrophenyl]malonate 
• 594844-71-0 (3-dimethylcarbamoyl-4-nitrophenyl)acetic acid methyl ester 
• 480451-75-0 5-chloro-N,N-dimethyl-2-nitrobenzamide 
• 2516-95-2 5-chloro-2-nitrobenzoic acid 

Downstream Products

• 1350468-91-5 methyl [3-(dimethylcarbamoyl)-4-({[4'-(trifluoromethyl)biphenyl-2-yl]carbonyl}amino)phenyl]acetate 
• 594844-27-6 2-(3-(dimethylcarbamoyl)-4-(4'-(trifluoromethyl)-[1,1'-biphenyl]-2-ylcarboxamido)phenyl)acetic acid 
• 1350468-90-4 ethyl 1R-({2-[3-(dimethylcarbamoyl)-4-({[4'-(trifluoromethyl)biphenyl-2-yl]carbonyl}amino)phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate 

Relevant articles and documents

2-PHENYL BENZOYLAMIDES

Compounds of Formula I that inhibit microsomal triglyceride transfer protein (MTP) and/or apolipoprotein B (Apo B) secretion and their uses in the treatment of diseases linked thereto in animals are described herein.

ESTER COMPOUND AND MEDICINAL USE THEREOF

A novel therapeutic agent for hyperlipidemia, which is an ester compound represented by the formula (1") (wherein ???R1 and R2 are each hydrogen atom or optionally substituted aryl, etc.; ???X is -COO- or -CON(R10)-; ???R3 and R4 are each hydrogen atom, C1-C6 alkyl or C1-C6 alkoxy, etc.; ???R5, R6 and R7 are each hydrogen atom, C1-C6 alkyl or C1-C6 alkoxy, etc.; ???R8 and R9 are each independently hydrogen atom, C1-C6 alkyl, -CON(R18)(R19) or -COO(R20), etc.; ???ring A, ring B and ring C are each independently aryl or heterocycle residue, etc.; ???Alk1 and Alk2 are each independently alkanediyl, etc.; ???l and m are each an integer of 0 or 1 to 3) or a prodrug thereof, or a pharmaceutically acceptable salt of either. The therapeutic agent selectively inhibits MTP in the small intestine, thus causes no such side effect as a fatty liver.