594845-77-9

Upstream product

• 594845-89-3 3-(tert-butyldimethylsilyloxymethyl)-1,2-cyclopentanedione 
• 594845-88-2 3-(tert-butyldimethylsilyloxymethyl)-1,2-cyclopentanediol 
• 594845-87-1 tert-butyl-(cyclopent-2-enylmethoxy)-dimethyl-silane 
• 13668-59-2 3-hydroxymethyl-cyclopentene 
• 594845-74-6 2-hydroxy-3-(hydroxymethyl)-cyclopent-2-en-1-one 

Relevant academic research and scientific papers

Asymmetric oxidation of 3-alkyl-1,2-cyclopentanediones. Part 2: Oxidative ring cleavage of 3-alkyl-1,2-cyclopentanediones: Synthesis of 2-alkyl-γ-lactone acids

Ti(OiPr)4/diethyl tartrate/tBuOOH system oxidizes 3-alkyl-1,2-cyclopentanediones resulting in hydroxylated ring cleavage products 2-alkyl-γ-lactone acids, in high enantioselectivity (～95% ee) and satisfactory isolated yields (up to 55%).