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Cinchonan, a group of alkaloids derived from the bark of the Cinchona tree, primarily consists of quinine, quinidine, cinchonine, and cinchonidine. These alkaloids have been historically significant for their antimalarial properties, with quinine being the most well-known for treating malaria. They also exhibit anti-inflammatory, antipyretic, and analgesic effects. In addition to their medicinal uses, cinchonan alkaloids have applications in the pharmaceutical industry as antimicrobial agents and in the chemical industry as catalysts in various reactions. However, due to potential side effects and the development of more effective synthetic drugs, their use in modern medicine has diminished, although they still hold relevance in certain therapeutic contexts and as research tools in chemical and pharmaceutical sciences.

5949-01-9

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5949-01-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5949-01-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,4 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5949-01:
(6*5)+(5*9)+(4*4)+(3*9)+(2*0)+(1*1)=119
119 % 10 = 9
So 5949-01-9 is a valid CAS Registry Number.

5949-01-9Downstream Products

5949-01-9Relevant academic research and scientific papers

Designing fluorinated cinchona alkaloids for enantioselective catalysis: Controlling internal rotation by a fluorine-ammonium ion gauche effect (ψNCCF)

Tanzer, Eva-Maria,Schweizer, W. Bernd,Ebert, Marc-Olivier,Gilmour, Ryan

, p. 2006 - 2013 (2012/03/27)

The C9 position of cinchona alkaloids functions as a molecular hinge, with internal rotations around the C8-C9 (τ1) and C9-C4′ (τ2) bonds giving rise to four low energy conformers (1; anti-closed, anti-open, syn-closed, and syn-open)

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