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Cinchonine hydrochloride, a stereoisomer of quinine, is a chemical compound extracted from the cinchona tree bark. It exhibits antimalarial and antipyretic properties, and due to its similar chemical structure to quinine, it functions as an antagonist of adenosine receptors and possesses antiarrhythmic effects. Furthermore, it is utilized as a resolving agent for chiral acids and a chiral ligand in asymmetric synthesis. Its cytotoxic effects on cancer cells have also garnered interest for potential cancer treatment applications.

5949-11-1

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5949-11-1 Usage

Uses

Used in Pharmaceutical Industry:
Cinchonine hydrochloride is used as an antimalarial and antipyretic agent for its ability to treat malaria and reduce fever.
Used in Cardiology:
It is used as an antiarrhythmic agent due to its antagonistic effects on adenosine receptors, which helps in managing irregular heartbeats.
Used in Organic Chemistry:
Cinchonine hydrochloride is used as a resolving agent for chiral acids, facilitating the separation of enantiomers, which is crucial in the synthesis of chiral compounds.
Used in Asymmetric Synthesis:
It serves as a chiral ligand in asymmetric synthesis, enabling the selective formation of one enantiomer over another, which is vital for producing enantiomerically pure compounds.
Used in Cancer Research:
Cinchonine hydrochloride is studied for its potential use as a cytotoxic agent against certain types of cancer, targeting and destroying cancer cells.

Check Digit Verification of cas no

The CAS Registry Mumber 5949-11-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,4 and 9 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5949-11:
(6*5)+(5*9)+(4*4)+(3*9)+(2*1)+(1*1)=121
121 % 10 = 1
So 5949-11-1 is a valid CAS Registry Number.
InChI:InChI=1/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/p+1/t13-,14+,18+,19-/m1/s1

5949-11-1 Well-known Company Product Price

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  • TCI America

  • (C0351)  Cinchonine Hydrochloride Hydrate  >80.0%(HPLC)

  • 5949-11-1

  • 25g

  • 690.00CNY

  • Detail

5949-11-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Cinchonine monohydrochloride hydrate

1.2 Other means of identification

Product number -
Other names L-CINCHONINE HYDROCHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5949-11-1 SDS

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