59507-52-7

Basic information

• Product Name: N-(3-bromobenzyl)cyclohexanamine
• Synonyms: CHEMBRDG-BB 6542504;UKRORGSYN-BB BBV-118516;(3-BROMOBENZYL)CYCLOHEXYLAMINE;(3-bromobenzyl)cyclohexylamine(SALTDATA: HCl)
• CAS NO: 59507-52-7
• Molecular Formula: C₁₃H₁₈BrN
• Molecular Weight: 268.1927
• Mol File: 59507-52-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 343.9°C at 760 mmHg
• Flash Point: 161.8°C
• Density: 1.29g/cm³
• Vapor Pressure: 6.82E-05mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: N-(3-bromobenzyl)cyclohexanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-bromobenzyl)cyclohexanamine(59507-52-7)
• EPA Substance Registry System: N-(3-bromobenzyl)cyclohexanamine(59507-52-7)

Safety Data

• Hazardous Substances Data: 59507-52-7(Hazardous Substances Data)

Upstream product

• 3132-99-8 m-bromobenzoic aldehyde 
• 108-91-8 cyclohexylamine 
• 823-78-9 meta-bromobenzyl bromide 

Relevant articles and documents

Design, Synthesis, and Structure-Activity Relationship of Economical Triazole Sulfonamide Aryl Derivatives with High Fungicidal Activity

Plant fungal diseases have caused great decreases in crop quality and yield. As one of the considerable agricultural diseases, cucumber downy mildew (CDM) caused by pseudoperonospora cubensis seriously influences the production of cucumber. Amisulbrom is a commercial agricultural fungicide developed by Nissan Chemical, Ltd., for the control of oomycetes diseases that is highly effective against CDM. However, the synthesis of amisulbrom has a high cost because of the introduction of the bromoindole ring. In addition, the continuous use of amisulbrom might increase the risk of resistance development. Hence, there is an imperative to develop active fungicides with new scaffolds but low cost against CDM. In this study, a series of 1,2,4-triazole-1,3-disulfonamide derivatives were designed, synthesized, and screened. Compound 1j showed a comparable fungicidal activity with amisulbrom, but it was low cost and ecofriendly. It has the potential to be developed as a new fungicide candidate against CDM. Further investigations of structure-activity relationship exhibited the structural requirements of 1,2,4-triazole-1,3-disulfonamide and appropriate modification in N-alkyl benzylamine groups with high fungicidal activity. This research will provide powerful guidance for the design of highly active lead compounds with a novel skeleton and low cost.

COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION

The subject matter of the present invention is novel families of compounds which are aromatic amine, imine, aminoadamantane and benzodiazepine derivatives, medicaments comprising same and the use thereof as inhibitors of the toxic effects of toxins with intracellular activity, such as, for example, ricin, and of viruses that use the internalization pathway for infecting cells.