5952-39-6

Usage

Structure

Consists of a butanedione backbone with a diphenylphosphinyl group attached at the 2 position.

Role

Commonly used as a ligand in coordination chemistry.

Applications

Potential applications in catalysis, organic synthesis, and materials science.

Safety Precautions

Important to handle with caution due to potential hazards to human health and the environment.

Upstream product

• 2129-89-7 diphenyl(methyl)phosphine oxide 
• 93-58-3 benzoic acid methyl ester 
• 1733-58-0 phenacyldiphenylphosphine oxide 
• 70-11-1 α-bromoacetophenone 
• 4559-70-0 Diphenylphosphine oxide 
• 959-28-4 1,4-diphenylbut-2-ene-1,4-dione 

Downstream Products

• 495-71-6 phenacylacetophenone 

Relevant academic research and scientific papers

P-C Bond formation via direct and three-component conjugate addition catalyzed by 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD)

The direct addition of P(O)-H bonds (dialkyl phosphites and diphenyl phosphonite) across various activated alkenes was catalyzed effectively by 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD). This is a mild, rapid and efficient protocol to generate P-C bonds.

Diphenylphosphinoyl-mediated synthesis of ketones

α-Diphenylphosphinoyl ketones are selectively and sequentially alkylated at the α-position. Double lithiation and selective alkylation occurs at the less stabilised γ-position. Dephosphinoylation of the alkylation products gives ketones. Mono-alkylation is selective, highly crystalline intermediates are formed and a one-pot strategy is possible. The method is ideally suited for the preparation of acid-sensitive ketones. The Royal Society of Chemistry 2006.