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(4Z)-4-[hydroxy(4-methylphenyl)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]-5-phenylpyrrolidine-2,3-dione, also known as PNU-142633, is a synthetic compound belonging to the pyrrolidine class. It features a hydroxyphenylmethylidene group and an imidazole group attached to a pyrrolidine-2,3-dione ring. (4Z)-4-[hydroxy(4-methylphenyl)methylidene]-1-[3-(1H-imidazol-1-yl)propyl]-5-phenylpyrrolidine-2,3-dione has been studied for its pharmacological properties, particularly as a potent and selective inhibitor of human neutrophil proteinase 3 (PR3), an enzyme crucial in the inflammatory response.

5955-27-1

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5955-27-1 Usage

Uses

Used in Pharmaceutical Industry:
PNU-142633 is used as an anti-inflammatory agent for the treatment of various inflammatory diseases. Its application is based on its ability to inhibit the activity of human neutrophil proteinase 3 (PR3), a key enzyme in the inflammatory process. By inhibiting PR3, PNU-142633 can potentially reduce inflammation and alleviate symptoms associated with inflammatory conditions.
Used in Antifungal Applications:
PNU-142633 is also being investigated for its potential as an antifungal agent. Its application in this field is due to its ability to target and inhibit specific fungal enzymes or proteins, which could help in the development of new antifungal treatments for various fungal infections.

Check Digit Verification of cas no

The CAS Registry Mumber 5955-27-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,5 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5955-27:
(6*5)+(5*9)+(4*5)+(3*5)+(2*2)+(1*7)=121
121 % 10 = 1
So 5955-27-1 is a valid CAS Registry Number.

5955-27-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (4Z)-4-[hydroxy-(4-methylphenyl)methylidene]-1-(3-imidazol-1-ylpropyl)-5-phenylpyrrolidine-2,3-dione

1.2 Other means of identification

Product number -
Other names 3-hydroxy-1-[3-(1H-imidazol-1-yl)propyl]-4-[(4-methylphenyl)carbonyl]-5-phenyl-1,5-dihydro-2H-pyrrol-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5955-27-1 SDS

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