595548-60-0Relevant academic research and scientific papers
Cobalt catalyzed sp3 C-H amination utilizing aryl azides
Villanueva, Omar,Weldy, Nina MacE,Blakey, Simon B.,MacBeth, Cora E.
, p. 6672 - 6675 (2015/10/28)
A dinuclear Co(ii) complex supported by a modular, tunable redox-active ligand system is capable of selective C-H amination to form indolines from aryl azides in good yields at low (1 mol%) catalyst loading. The reaction is tolerant of medicinally relevant heterocycles, such as pyridine and indole, and can be used to form 5-, 6-, and 7-membered rings. The synthetic versatility obtained using low loadings of an earth abundant transition metal complex represents a significant advance in catalytic C-H amination technology.
Intramolecular Ir(I)-catalyzed benzylic C-H bond amination of ortho-substituted aryl azides
Sun, Ke,Sachwani, Rachna,Richert, Kathleen J.,Driver, Tom G.
supporting information; experimental part, p. 3598 - 3601 (2011/02/23)
Image Persented Iridium(I) catalyzes the intramolecular benzylic C-H bond amination of ortho-homobenzyl-substituted aryl azides to produce indolines at 25 °C.
