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595597-05-0

diethyl [(4-aminophenyl)(hydroxy)methyl]phosphonate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 595597-05-0 Structure

  • Basic information

    1. Product Name: diethyl [(4-aminophenyl)(hydroxy)methyl]phosphonate
    2. Synonyms: diethyl [(4-aminophenyl)(hydroxy)methyl]phosphonate
    3. CAS NO:595597-05-0
    4. Molecular Formula:
    5. Molecular Weight: 259.242
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 595597-05-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: diethyl [(4-aminophenyl)(hydroxy)methyl]phosphonate(CAS DataBase Reference)
    10. NIST Chemistry Reference: diethyl [(4-aminophenyl)(hydroxy)methyl]phosphonate(595597-05-0)
    11. EPA Substance Registry System: diethyl [(4-aminophenyl)(hydroxy)methyl]phosphonate(595597-05-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 595597-05-0(Hazardous Substances Data)

595597-05-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 595597-05-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,5,5,9 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 595597-05:
(8*5)+(7*9)+(6*5)+(5*5)+(4*9)+(3*7)+(2*0)+(1*5)=220
220 % 10 = 0
So 595597-05-0 is a valid CAS Registry Number.

595597-05-0Relevant articles and documents

Synthesis and evaluation of phosphorus containing, specific CDK9/CycT1 inhibitors

Németh, Gábor,Greff, Zoltán,Sipos, Anna,Varga, Zoltán,Székely, Rita,Sebestyén, Mónika,Jászay, Zsuzsa,Béni, Szabolcs,Nemes, Zoltán,Pirat, Jean-Luc,Volle, Jean-No?l,Virieux, David,Gyuris, ágnes,Kelemenics, Katalin,áy, éva,Minarovits, Janos,Szathmary, Susan,Kéri, Gy?rgy,Orfi, László

, p. 3939 - 3965 (2014/06/09)

Although there is a significant effort in the design of a selective CDK9/CycT1 inhibitor, no compound has been proven to be a specific inhibitor of this kinase so far. The aim of this research was to develop novel and selective phosphorus containing CDK9/CycT1 inhibitors. Molecules bearing phosphonamidate, phosphonate, and phosphinate moieties were synthesized. Prepared compounds were evaluated in an enzymatic CDK9/CycT1 assay. The most potent molecules were tested in cell-based toxicity and HIV proliferation assays. Selectivity of shortlisted compounds against CDKs and other kinases was tested. The best compound was shown to be a highly specific, ATP-competitive inhibitor of CDK9/CycT1 with antiviral activity.

Aromatic phosphonates inhibit the lysophospholipase D activity of autotaxin

Jiang, Guowei,Madan, Damian,Prestwich, Glenn D.

scheme or table, p. 5098 - 5101 (2011/10/09)

Autotaxin (ATX) is an attractive target for the anticancer therapeutics that inhibits angiogenesis, invasion and migration. ATX is an extracellular lysophospholipase D that hydrolyzes lysophosphatidylcholine to form the bioactive lipid lysophosphatidic ac

AZOLE COMPOUNDS

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Page 47, (2010/02/09)

The present invention provides a compound represented by the formula (I) wherein R1 is a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, an optionally substituted hydroxy group, an optionally substituted thiol group or an optionally substituted amino group, A is an optionally substituted cyclic amino group or -NR2-W-D wherein R2 is a hydrogen atom or an alkyl group, W is a bond or a divalent acyclic hydrocarbon group, and D is an optionally substituted cyclic group, an optionally substituted amino group or an optionally substituted acyl group, B is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, X is an oxygen atom, a sulfur atom or an optionally substituted nitrogen atom, and Y is a bond or a divalent acyclic hydrocarbon group, or a salt thereof, which is useful for the prophylaxis or treatment of diabetic neuropathy and the like.

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