595604-83-4

Upstream product

• 595604-77-6 trans-1-(2-furyl)-2-phenyl-cyclohexanol 
• 595604-79-8 (6R,7R)-7-phenyl-1-oxaspiro[5.5]undec-3-ene-2,5-dione 
• 595604-78-7 (6S,7S)-2-Hydroxy-7-phenyl-1-oxa-spiro[5.5]undec-3-en-5-one 
• 98919-68-7 (1R,2S)-trans-2-phenylcyclohexanol 
• 1444-65-1 (2S)-2-phenyl-1-cyclohexanone 
• 595604-80-1 C₂₁H₂₂O₃ 

Downstream Products

• 1444-65-1 (2S)-2-phenyl-1-cyclohexanone 
• 499971-02-7 (2S,3S,6R)-4-oxatricyclo[5.2.1.0^2,6]dec-3-ol-8-ene 

Relevant academic research and scientific papers

Synthesis of novel chiral spirodione, (6R,7R)-7-phenyl-1-oxaspiro[5.5]undec-3-ene-2,5-dione: Application to the asymmetric Diels-Alder reaction with high π-facial selectivity

The synthesis of the title spirodione, a new class of auxiliary based chiral synthon using (-)-trans-2-phenylcyclohexanol and its application to the asymmetric Diels-Alder reaction are described. Methodology for detachment of the chiral auxiliary from the cycloadduct has been developed.