59590-68-0

Usage

Uses

Used in Agricultural Industry:
(1-amino-2-methylpropan-2-yl)phosphonic acid is used as a key component in herbicides, fungicides, and insecticides for its ability to control pests and diseases in crops.
Used in Pharmaceutical Industry:
(1-amino-2-methylpropan-2-yl)phosphonic acid is used in the production of pharmaceuticals as a key intermediate in the synthesis of various organic compounds.
Used in Water Treatment Industry:
(1-amino-2-methylpropan-2-yl)phosphonic acid is used for its strong chelating properties in water treatment, metal chelation, and corrosion inhibition applications.
Used in Material Development:
(1-amino-2-methylpropan-2-yl)phosphonic acid has potential uses in the development of new materials for various industrial and consumer applications.

Upstream product

• 684286-47-3 diethyl 2-amino-1,1-dimethyl-ethylphosphonate hydrochloride 
• 59590-62-4 Bis(dimethylamino)-α,α-dimethyl-β-aminoaethylphosphonat 

Downstream Products

• 1056157-81-3 C₂₄H₂₆NO₅P 

Relevant academic research and scientific papers

Method and compositions for identifying anti-HIV therapeutic compounds

Methods are provided for identifying anti-HIV therapeutic compounds substituted with carboxyl ester or phosphonate ester groups. Libraries of such compounds are screened optionally using the novel enzyme GS-7340 Ester Hydrolase. Compositions and methods relating to GS-7340 Ester Hydrolase also are provided.

PHOSPHONATE ANALOGS OF HIV INTEGRASE INHIBITOR COMPOUNDS

Novel HIV integrase inhibitor compounds having at least one phosphonate group, protected intermediates thereof, and methods for inhibition of HIV-integrase are disclosed.

Method and compositions for identifying anti-HIV therapeutic compounds

Methods are provided for identifying anti-HIV therapeutic compounds substituted with carboxyl ester or phosphonate ester groups. Libraries of such compounds are screened optionally using the novel enzyme GS-7340 Ester Hydrolase. Compositions and methods relating to GS-7340 Ester Hydrolase also are provided.

PRE-ORGANIZED TRICYCLIC INTEGRASE INHIBITOR COMPOUNDS

Tricyclic compounds according to the structure below, protected intermediates thereof, and methods for inhibition of HIV-integrase are disclosed. Formula (I). Al and A2 are moieties forming a five, six, or seven membered ring. L is a bond or a linker connecting a ring atom of Ar to N. X is O, S, or substituted nitrogen. Ar is aryl or heteroaryl. Q is N, +NR, or CR4. The aryl carbons may be independently substituted with substituents other than hydrogen. The compounds may include prodrug moieties covalently attached at any site.