59592-33-5

Usage

Uses

Used in Pharmaceutical Industry:
Metronidazole is used as an antibiotic for treating bacterial and parasitic infections, such as bacterial vaginosis, trichomoniasis, and certain skin, bone, and joint infections. Its application in this industry is due to its ability to effectively target and eliminate harmful microorganisms, providing relief and treatment for the infected individual.
Used in Research and Development:
In the field of research and development, metronidazole serves as a valuable compound for studying the mechanisms of action against various microorganisms. Its use in this context aids in the advancement of medical knowledge and the development of new treatments for infectious diseases.
Used in Veterinary Medicine:
Metronidazole is also utilized in veterinary medicine to treat infections in animals, showcasing its broad-spectrum efficacy. Its application in this industry is due to its ability to address a range of infections in different species, contributing to the overall health and well-being of animals.

InChI:InChI=1/C11H15N3S/c1-15-7-6-8(12)11-13-9-4-2-3-5-10(9)14-11/h2-5,8H,6-7,12H2,1H3,(H,13,14)/p+1/t8-/m1/s1

Upstream product

• 63-68-3 L-methionine 
• 95-54-5 1,2-diamino-benzene 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 133703-78-3 tert-butyl 1-(2-aminophenylamino)-4-(methylthio)-1-oxobutan-2-ylcarbamate 
• 93000-03-4 N-(t-butoxycarbonyl)methionine 

Relevant academic research and scientific papers

Facile synthesis, characterization and antimicrobial activity of 2-alkanamino Benzimidazole derivatives

Benzimidazole derivatives are known to represent a class of medicinally important compounds which are extensively used in drug design and catalysis. A series of 2-substituted benzimidazole derivatives 10a-i was herein synthesized from the reaction of o-phenylenediamine with some amino acids using ameliorable pathway. The chemical structures of the synthesized compounds were confirmed by IR, UV, 1H-NMR, 13C-NMR, Mass spectral and analytical data. The compounds were investigated for their antimicrobial activity alongside gentamicin clinical standard. The results showed that this skeletal framework exhibited marked potency as antimicrobial agents. The most active compound was 1H-benzo[d]imidazol-2-yl)methanamine, 10a.

Synthesis and biological activity of novel thiourea derivatives as carbonic anhydrase inhibitors

A new series of chiral thiourea derivatives (5a-5c) and thiourea containing benzimidazole moieties (9b-9e) were synthesized from different amino acids (L-valine, L-isoleucine, L-methionine, L-phenylalanine, and D-phenylglycine). The compounds were charact

Synthesis of benzimidazoles from amino acids with solvent-free melting method

By using low cost and readily available amino acids as the synthetic blocks, a series of 2-Aminomethyl-benzimidazole are synthesized with solvent-free melting method. While the condensation of aspartic acid (or asparagine) with o-diaminobenzene gives the

Discovery of small molecule human FPR1 receptor antagonists

The identification of two novel series of formyl peptide receptor 1 (FPR1) antagonists are reported, represented by methionine benzimidazole 6 and diamide 7. Both series specifically inhibited the binding of labelled fMLF to hrFPR1 and selectively antagonized FPR1 function in human neutrophils, making them useful in vitro validation tools for the target.