59608-57-0 Usage
Uses
Used in Pharmaceutical Industry:
3-Benzyl[1,3]thiazolo[3,2-a]benzimidazole is used as a key intermediate in the synthesis of various pharmaceutical compounds for therapeutic applications. Its unique structure and potential biological activities contribute to the development of novel drugs with improved efficacy and safety profiles.
Used in Medicinal Chemistry Research:
3-Benzyl[1,3]thiazolo[3,2-a]benzimidazole serves as a valuable research tool in medicinal chemistry, enabling scientists to explore its potential pharmacological activities and investigate its interactions with biological targets. 3-benzyl[1,3]thiazolo[3,2-a]benzimidazole can be used to design and optimize new drug candidates with specific therapeutic properties.
Used in Drug Discovery:
3-Benzyl[1,3]thiazolo[3,2-a]benzimidazole is utilized in drug discovery processes to identify and develop new therapeutic agents. Its unique structure and potential biological activities make it a promising starting point for the design of innovative drugs targeting various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 59608-57-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,6,0 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 59608-57:
(7*5)+(6*9)+(5*6)+(4*0)+(3*8)+(2*5)+(1*7)=160
160 % 10 = 0
So 59608-57-0 is a valid CAS Registry Number.
59608-57-0Relevant academic research and scientific papers
Copper- and Palladium-Catalyzed Cross-Coupling Reactions for the Synthesis of N-Fused Benzo[4,5]imidazo[2,1-b]thiazole Derivatives via Substituted trans-1,2-Diiodoalkenes, 1H-Benzo[d]imidazole-2-thiols, and Halobenzenes
Shen, Guodong,Yang, Bingchuan,Huang, Xianqiang,Hou, Yaxin,Gao, Huan,Cui, Jichun,Cui, Chuansheng,Zhang, Tongxin
, p. 3798 - 3805 (2017/04/11)
Two transition metal (Cu and Pd)-catalyzed C-S, C-N, and C-C bond cross-coupling reactions for the preparation of N-fused benzo[4,5]imidazo[2,1-b]thiazole derivatives were developed. A variety of 3-substituted and 2,3-disubstituted benzo[4,5]imidazo[2,1-b]thiazoles were efficiently and conveniently synthesized from the coupling reaction via trans-1,2-diiodoalkenes, 1H-benzo[d]imidazole-2-thiols, and halobenzenes in moderate to excellent yields.
Pd-Cu catalyzed heterocyclization during Sonogashira coupling: Synthesis of 3-benzylthiazolo[3,2-a]benzimidazole
Heravi, Majid M.,Keivanloo, Ali,Rahimizadeh, Mohammad,Bakavoli, Mehdi,Ghassemzadeh, Mitra
, p. 5747 - 5749 (2007/10/03)
The reaction of 2-mercaptopropargyl benzimidazole with various iodobenzenes catalyzed by Pd-Cu leads to the formation of 3-benzylthiazolo[3,2-a] benzimidazoles.