596107-66-3

Upstream product

• 596107-62-9 C₄₆H₃₀N₂O₄ 
• 849060-01-1 C₃₄H₂₀Cl₂N₂O₆ 
• 849060-00-0 C₃₄H₂₀Cl₂N₂O₄ 
• 457625-37-5 3,3'-bis(methoxycarbonyl)-6,6'-diphenyl-2,2'-bipyridine 
• 457625-39-7 3,3'-bis(hydroxymethyl)-6,6'-diphenyl-2,2'-bipyridine 
• 25677-69-4 2,9-diphenyl-1,10-phenanthroline 
• 596107-68-5 C₃₄H₂₂N₂O₆ 

Downstream Products

• 746-46-3 (R)-1,1'-binaphthyl-2,2'-dicarboxylic acid 

Relevant academic research and scientific papers

A new approach to axially chiral bipyridine N,N′-dioxides bearing aromatic substituents and their use for catalytic asymmetric allylation of aldehydes with allyl(trichloro)silane

Palladium-catalyzed cross-coupling of bipyridine N,N′-dioxide 6,6′-dichloride (Rnap,Rpyr)-1 with the aryl Grignard reagents opened a new approach to axially chiral bipyridine N,N′-dioxides (R)-2 bearing a variety of aryl groups at th

A new synthetic route to enantiomerically pure axially chiral 2,2′-bipyridine N,N′-dioxides. Highly efficient catalysts for asymmetric allylation of aldehydes with allyl(trichloro)silanes

New axially chiral 2,2′-bipyridine N,N′-dioxides 1 were obtained in an enantiomerically pure form by way of cyclic diesters 6 or 7 which were formed by the esterification of diols 2 with (R)-2,2′-bis(chlorocarbonyl)-1,1′-binaphthalene (5). Epimerization of the kinetic products at the ester formation (Rnap,Spyr)-6 to the thermodynamically stable isomers (Rnap,Rpyr)-7 was observed in refluxing toluene or in the presence of trifluoroacetic acid. One of the N,N′-dioxides 1a which is substituted with phenyl groups at the 6 and 6′ positions was found to be highly catalytically active and enantioselective for the asymmetric allylation of aldehydes with allyl(trichloro)silane giving homoallyl alcohols.