596108-49-5Relevant academic research and scientific papers
Synthesis and biological evaluation of novel flavone-8-acetic acid derivatives as reversible inhibitors of aminopeptidase N/CD13
Bauvois, Brigitte,Puiffe, Marie-Line,Bongui, Jean-Bernard,Paillat, Sandrine,Monneret, Claude,Dauzonne, Daniel
, p. 3900 - 3913 (2007/10/03)
The cell surface aminopeptidase N (APN/CD13), overexpressed in tumor cells, plays a critical role in angiogenesis. However, potent, selective, and, particularly, noncytotoxic inhibitors ot this protein are lacking, and the present work was undertaken with
