59611-60-8Relevant academic research and scientific papers
General and chemoselective bisphosphonylation of secondary and tertiary amides
Wang, Ai-E.,Chang, Zong,Sun, Wei-Ting,Huang, Pei-Qiang
, p. 732 - 735 (2015)
With Tf2O as the activation reagent, a mild and general method has been developed for the bisphosphonylation of both secondary and tertiary amides. The protocol is highly efficient and chemoselective, and it tolerates a number of sensitive functional groups such as cyano, ester, and aldehyde groups.
