596119-92-5Relevant articles and documents
Synthesis and crystal structure of hydrogenated pyrazino [2,1-a]isoquinoline derivatives
Zawadzka,Leniewski,Maurin,Wojtasiewicz,Siwicka,Czarnocki
, p. 565 - 576 (2007/10/03)
Racemic amino acids (Ala and Val) were used in order to optimize the procedures and to check the stereochemical outcome of the synthesis of tetrahydroisoquinoline derivatives. The key step introduced the Pictet-Spengler condensation on ketoamides 4a and 4