5962-41-4Relevant academic research and scientific papers
Phospholipid derivatives of phosphono-carboxylic acids, the production of said derivatives and the use of said derivatives as antiviral medicaments
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, (2008/06/13)
PCT No. PCT/EP96/05647 Sec. 371 Date Aug. 27, 1998 Sec. 102(e) Date Aug. 27, 1998 PCT Filed Dec. 16, 1996 PCT Pub. No. WO97/22613 PCT Pub. Date Jun. 26, 1997The present invention concerns new lipid derivatives of phosphonocarboxylic acids of the general formula I, in which the meaning of the symbols is elucidated in the description, tautomers thereof and their physiologically tolerated esters and salts of inorganic or organic bases as well as processes for the production thereof and pharmaceutical agents containing these compounds.
PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING COMPULSIVE DISORDERS USING NAALADASE INHIBITORS
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, (2008/06/13)
The present invention relates to a pharmaceutical composition and a method for treating a compulsive disorder using a NAALADase inhibitor.
Phosphonylation process
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, (2008/06/13)
A process for the production of a phosphono organo carboxylic acid, said process comprising a reaction stage wherein an unsaturated carboxylic acid [or a salt or an anhydride of said acid], is heated with a chlorophosphorus reaction product to produce a mixture including a phosphono organo carboxylic acid chloride, and a hydrolysis stage wherein said mixture is treated with an aqueous medium to produce said phosphono organo carboxylic acid. The process provides a relatively simple means of making the acid in high yields.
PHOSPHONOACYL PROLINES AND RELATED COMPOUNDS
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, (2008/06/13)
New phosphonoacyl prolines and related compounds have the general formula STR1 wherein R 1 and R 2 each is hydrogen, lower alkyl, lower alkenyl, unsustituted or substituted phenyl-lower alkyl, or a metal ion;R 3 is hydrogen or lower alkyl; R 4 is hydrogen, lower alkyl, phenyl-lower alkyl or a metal ion; andN IS 0 OR 1. These compounds are useful as hypotensive agents.
