59640-46-9Relevant academic research and scientific papers
SUBSTITUTED PYRROLOPYRIDINES AS ATR INHIBITORS
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Page/Page column 39, (2019/04/10)
The disclosure includes compounds of Formula (I) wherein A, W, m, R5, R6, R7, and R8, are defined herein. Also disclosed is a method for treating a neoplastic disease with these compounds.
PROCESS FOR THE SYNTHESIS OF 6-CHLOROMETHYLURACIL
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Page/Page column 13; 14, (2019/09/18)
The invention relates to a process for the synthesis of 6-chloromethyluracil (6-(chloromethyl)pyrimidin-2,4(1H,3H)-dione) from ethyl 4-chloroacetoacetate and S- methylisothiourea hemisulfate via isolation of the novel intermediate 6- (chloromethyl)-6-hydroxy-2-(methylthio)-5,6-dihydropyrimidin-4(1H)-one, and its subsequent treatment with aqueous sulfuric acid. Formula (I).
