596803-56-4Relevant academic research and scientific papers
A concise approach for the synthesis of 3-iodoindoles and 3-iodobenzo[b]furans via Ph3P-catalyzed iodocyclization
Li, Yin-Long,Li, Jian,Yu, Sheng-Nan,Wang, Ji-Bo,Yu, Yan-Min,Deng, Jun
, p. 8271 - 8277 (2015)
A variety of 3-iodoindole and 3-iodobenzo[b]furan derivatives were conveniently prepared from the corresponding 2-alkynylanilines and 2-alkynylphenols through Ph3P-catalyzed iodocyclization in the presence of N-iodosuccinimide (NIS). This proto
IPy2BF4-promoted intramolecular addition of masked and unmasked anilines to alkynes: Direct assembly of 3-iodoindole cores
Barluenga, Jose,Trincado, Monica,Rubio, Eduardo,Gonzalez, Jose M.
, p. 2406 - 2409 (2007/10/03)
All at once! Indoles can be assembled and iodinated in a one-pot process (see scheme) from anilines and their derivatives. This metal-free addition of nitrogen compounds to alkynes is a clean reaction that is promoted by iodonium cations. Such a process p
