596828-48-7Relevant academic research and scientific papers
Synthesis and inhibitory activity of ubiquinone-acetogenin hybrid inhibitor with bovine mitochondrial complex I
Yabunaka, Hiromi,Abe, Masato,Kenmochi, Atsushi,Hamada, Takeshi,Nishioka, Takaaki,Miyoshi, Hideto
, p. 2385 - 2388 (2007/10/03)
To elucidate the inhibitory action of acetogenins, the most potent inhibitors of mitochondrial complex I, we synthesized an acetogenin analogue which possesses a ubiquinone ring (i.e., the physiological substrate of complex I) in place of the α,β-unsatura
