596829-29-7

Upstream product

• 596829-26-4 Pentanedioic acid (2R,3S)-5,7-bis-benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-chroman-3-yl ester (2R,3S,4S)-5,7-bis-benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-4-(2-ethoxy-ethoxy)-chroman-3-yl ester 

Downstream Products

• 51196-37-3 3,4-cis-(+)-catechin-(4β->8)-(+)-catechin 

Relevant academic research and scientific papers

Stereoselection of 3,4-cis and 3,4-trans catechin and catechin condensation under intramolecular coupling method

A high level of stereoselection between 3,4-cis and 3,4-trans catechin-catechin condensation under intramolecular coupling method has been realized by changing the diester linker between the nucleophile and the electrophile. The azelaic acid linker gave exclusively 3,4-trans catechin-catechin dimer, whereas glutaric acid linker gave 3,4-cis catechin-catechin dimer as the sole product.

Synthetic studies of proanthocyanidins. Part 3: Stereoselective 3,4-cis catechin and catechin condensation by TMSOTf-catalyzed intramolecular coupling method

TMSOTf-catalyzed intramolecular condensation for catechin and epicatechin units are described. A potential electrophile and a nucleophile were connected with diester linkers and TMSOTf-catalyzed condensation was examined. In comparison with intermolecular