59694-51-8

Basic information

• Product Name: 7-AMino-5-chloroindole-2-carboxylic acid ethyl ester
• Synonyms: 7-AMino-5-chloroindole-2-carboxylic acid ethyl ester;ETHYL 7-AMINO-5-CHLORO-1H-INDOLE-2-CARBOXYLATE
• CAS NO: 59694-51-8
• Molecular Formula: C11H11ClN2O2
• Molecular Weight: 238.67024
• Mol File: 59694-51-8.mol

Chemical Properties

• Melting Point: 220 °C
• Boiling Point: 454.7±40.0 °C(Predicted)
• Appearance: /
• Density: 1.399±0.06 g/cm3(Predicted)
• PKA: 14.78±0.30(Predicted)
• CAS DataBase Reference: 7-AMino-5-chloroindole-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-AMino-5-chloroindole-2-carboxylic acid ethyl ester(59694-51-8)
• EPA Substance Registry System: 7-AMino-5-chloroindole-2-carboxylic acid ethyl ester(59694-51-8)

Safety Data

• Hazardous Substances Data: 59694-51-8(Hazardous Substances Data)

Upstream product

• 91119-27-6 5-chloro-7-nitro-1H-indole-2-carboxylic acid ethyl ester 

Relevant articles and documents

Process for dyeing keratinous fibers with aminoindoles and oxidation dye precursors at basic Ph's and dyeing agents

The invention relates to a process for dyeing keratinous fibres, which consists in applying to these fibres a composition containing, in a suitable medium for dyeing, at least one coupler of formula: STR1 where R1 denotes hydrogen or alkyl, R2 and R3 denote hydrogen, alkyl, COOR' where R' is alkyl or hydrogen, at least one of the groups R2 and R3 denoting hydrogen, R4 denotes hydrogen, alkyl, hydroxyalkyl, polyhydroxyalkyl or aminoalkyl, Z1 and Z2 denote hydrogen, alkyl, hydroxyl, halogen, alkoxy, at least one of the groups Z1 and Z2 is other than hydrogen at least one oxidation dye precursor, at least one oxidizing agent, the pH of the composition applied to the fibres being higher than 7.

Method for dyeing keratinous fibres using an aminoindole in combination with a quinone derivative

Method for dyeing keratinous fibres, characterized in that at least one composition (A) containing at least one aminoindole in a medium appropriate for dyeing is applied to these fibres, the application of the composition (A) being preceded or followed by the application of a composition (B) containing, in a medium appropriate for dyeing, at least one quinone derivative chosen from ortho- or para-benzoquinones, ortho- or para-benzoquinone monoimines or diimines, 1,2- or 1,4-naphthoquinones, ortho- or para-benzoquinone sulphonimides, α,ω-alkylene-bis-1,4-benzoquinones, or 1,2- or 1,4-naphthoquinone monoimines or diimines, the aminoindoles and the quinone derivatives being chosen such that the difference in redox potential ΔE between the redox potential Ei of the aminoindoles, determined at pH 7 in a phosphate medium on a vitreous carbon electrode by voltametry, and the redox potential Eq of the quinone derivative, determined at pH 7 in a phosphate medium by polarography on a mercury electrode relative to the saturated calomel electrode, in such that

Synthesis of Isomeric Benzodipyrroles

Ethyl aminoindole-2-carboxylates (2), obtained by catalytic reduction of ethyl nitroindole-2-carboxylates (1) using Raney nickel, when subjected to Japp-Klingemann reaction furnish the respective indolylhydrazones (3).The latter undergo cyclization with H2SO4 to yield different isomeric benzodipyrroles (4-6).