59722-22-4

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
1-(2-METHYLPHENOXY)-2-PROPANAMINE is used as a building block and intermediate for the synthesis of various pharmaceuticals and agrochemicals. Its role in these applications is attributed to its chemical structure, which allows for the creation of a diverse range of compounds with potential therapeutic and pesticidal properties.
Used in the Production of Crosslinked Polyacrylates:
In the polymer industry, 1-(2-METHYLPHENOXY)-2-PROPANAMINE is used as a crosslinking agent in the production of crosslinked polyacrylates. Its function in this application is to create a network of chemical bonds between polymer chains, enhancing the material's mechanical properties, such as strength, elasticity, and durability.
Used in the Synthesis of Organic Pigments:
1-(2-METHYLPHENOXY)-2-PROPANAMINE is also utilized in the synthesis of organic pigments, where it contributes to the development of pigments with specific color characteristics and properties. Its involvement in this process is due to its ability to form stable complexes with other molecules, resulting in pigments with enhanced color intensity and stability.
Used in Rubber Chemicals Production:
In the rubber industry, 1-(2-METHYLPHENOXY)-2-PROPANAMINE is used in the production of rubber chemicals, where it plays a role in improving the rubber's performance characteristics, such as its resistance to wear, tear, and environmental factors.
Used in Textile Auxiliaries:
1-(2-METHYLPHENOXY)-2-PROPANAMINE is employed in the textile industry as a component of textile auxiliaries, where it contributes to the enhancement of fabric properties, such as softness, durability, and resistance to stains and abrasion.
Used in Surfactant Production:
In the production of surfactants, 1-(2-METHYLPHENOXY)-2-PROPANAMINE is used to improve the performance of these compounds, which are essential in various industries, including cosmetics, detergents, and industrial cleaning. Its role in surfactant production is to enhance the surfactant's ability to reduce surface tension, leading to improved cleaning and emulsifying properties.

InChI:InChI=1/C10H15NO/c1-8-5-3-4-6-10(8)12-7-9(2)11/h3-6,9H,7,11H2,1-2H3

Upstream product

• 13662-01-6 o-tolyloxy-acetone 
• 95-48-7 ortho-cresol 

Relevant academic research and scientific papers

Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes

Ventricular cardiac arrhythmia (VA) arises in acquired or congenital heart disease. Long QT syndrome type-3 (LQT3) is a congenital form of VA caused by cardiac sodium channel (INaL) SCN5A mutations that prolongs cardiac action potential (AP) and enhances INaL current. Mexiletine inhibits INaL and shortens the QT interval in LQT3 patients. Above therapeutic doses, mexiletine prolongs the cardiac AP. We explored structure-activity relationships (SAR) for AP shortening and prolongation using dynamic medicinal chemistry and AP kinetics in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Using patient-derived LQT3 and healthy hiPSC-CMs, we resolved distinct SAR for AP shortening and prolongation effects in mexiletine analogues and synthesized new analogues with enhanced potency and selectivity for INaL. This resulted in compounds with decreased AP prolongation effects, increased metabolic stability, increased INaL selectivity, and decreased avidity for the potassium channel. This study highlights using hiPSC-CMs to guide medicinal chemistry and "drug development in a dish".

Amino-acid amide derivatives, agricultural or horticultural fungicides, and method for producing the same

The present invention provides an agricultural or horticultural fungicide including an effective amount of an amino-acid derivative represented by the formula: STR1 wherein R1 represents a lower alkyl group (optionally having at least one same or different substituent of a halogen atom, an alkoxy group, and a cyano group), R2 represents an ethyl group, or an n-propyl group, R3 represents a hydrogen atom or a lower alkyl group, R4 represents a hydrogen atom, R5, R6, and R7 independently represent a hydrogen atom or a lower alkyl group, R8 represents a hydrogen atom, or a lower alkyl group, Z1 and Z2 independently represent an oxygen atom or a sulfur atom, Z3 represents an oxygen atom, or a sulfur atom, Q represents a phenyl group, m represents an integer from 0 to 2, and n represents 0 or 1. The amino-acid amide derivatives according to the present invention exhibit superior control of cucumber downy mildew (Pseudoperonospora cubensis), tomato late blight (Phytophthora infestans), and grape downy mildew (Plasmopara viticola), and are effective for potato late blight (Phytophthora infestans). In addition, the agricultural or horticultural fungicides of the present invention are also characterized in that they are not harmful chemicals and exhibit excellent characteristics such as systemic action, residual activity, and persistence after rain-fall.