597540-69-7Relevant academic research and scientific papers
Stereocontrolled synthesis of a potent agonist of group II metabotropic glutamate receptors, (+)-LY354740, and its related derivatives
Ohfune, Yasufumi,Demura, Takashi,Iwama, Seiji,Matsuda, Hiromi,Namba, Kosuke,Shimamoto, Keiko,Shinada, Tetsuro
, p. 5431 - 5434 (2007/10/03)
Efficient synthesis of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740: 1) and its structurally related analogs (-)-2 and (-)-3 has been accomplished starting with (1S,2R)-1-amino-2-hydroxycyclopentane- or cyclohexanecarboxylic acid (4 or 17 ) via an intramolecular cyclopropanation of α-diazo acetamide.
