597541-58-7

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 597541-56-5 (-)-{3-methyl-3-[2-(3,4,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethyl]oxiranyl}methanol 
• 5153-92-4 sclareol oxide 
• 112920-24-8 4-(1,1,5,6-tetramethyl-1,2,3,4-tetrahydro-7-naphthyl)butan-2-one 
• 175792-69-5 13-acetoxy-14,15-dinor-isofregenedane 
• 556834-73-2 (2S,4aS,8aS)-4-(3-Hydroxy-butyl)-3,4a,8,8-tetramethyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-2-ol 
• 597541-57-6 4-((1R,4aS,8aS)-2-Hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl)-butan-2-ol 
• 597541-53-2 4-(3,4,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-butan-2-ol 
• 556811-03-1 7β,13-diacetoxy-14,15-dinor-8-labdene 
• 556811-02-0 7β,13-diacetoxy-14,15-dinor-8-labdene 
• 102867-65-2 labd-7-en-12-acetyl-17-oic acid methyl ester 
• 515-03-7 sclareol 

Relevant academic research and scientific papers

Synthesis and absolute configuration of (-)-chrysolic acid and (+)-isofregenedol

An efficient synthesis of (-)-chrysolic acid and (+)-isofregenedol has been achieved from zamoranic acid and sclareol. The characteristic tetrahydronaphtalenic system was obtained by use of a cationic rearrangement of bicyclic systems adequately functionalized. The absolute configuration of the natural products was established using Sharpless asymmetric epoxidation.