597557-40-9Relevant academic research and scientific papers
Asymmetric synthesis of the highly potent anti-metastatic prostacyclin analogue cicaprost and its isomer isocicaprost
Lerm, Marco,Gais, Hans-Joachim,Cheng, Kejun,Vermeeren, Cornelia
, p. 9653 - 9667 (2007/10/03)
An asymmetric synthesis of the anti-metastatic prostacyclin analogue cicaprost and a formal one of its isomer isocicaprost by a new route are described. A key step of these syntheses is the coupling of a chiral bicyclic C6-C14 ethynyl building block with
