597558-64-0

Upstream product

• 2216-51-5 (-)-menthol 
• 597558-63-9 (+/-)-2-methoxy-2-(9-phenanthryl)propionic acid 
• 71112-64-6 9-phenanthrylmagnesium bromide 
• 597558-61-7 (+/-)-methyl 2-hydroxy-2-(9-phenanthryl)propionate 
• 597558-62-8 (+/-)-methyl 2-methoxy-2-(9-phenanthryl)propionate 

Relevant academic research and scientific papers

Synthesis and analytical properties of (S)-(+)-2-methoxy-2-(9-phenanthryl)propionic acid

2-Methoxy-2-(9-phenanthryl)propionic acid was synthesized as a novel chiral resolving agent. The absolute configuration of (+)-2-methoxy-2-(9-phenanthryl)propionic acid was determined to be S by using X-ray structural analysis of the (1R,2S,5R)-menthyl ester. In the crystal, the methoxyl and carbonyl groups of the ester are in a syn-periplanar position. The syn-periplanar conformations of (1R,2S,5R)-menthyl esters were also observed by the NMR analyses in CDCl3. The utility of (S)-(+)-2-methoxy-2-(9-phenanthryl)propionic acid was exemplified by the resolution of (±)-3-octanol.