59776-24-8

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 6-[(3,4-dimethylphenyl)amino]-3-methyl-
• CAS NO: 59776-24-8
• Molecular Formula: C13H15N3O2
• Molecular Weight: 245.281
• Mol File: 59776-24-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 6-[(3,4-dimethylphenyl)amino]-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 6-[(3,4-dimethylphenyl)amino]-3-methyl-(59776-24-8)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 6-[(3,4-dimethylphenyl)amino]-3-methyl-(59776-24-8)

Safety Data

• Hazardous Substances Data: 59776-24-8(Hazardous Substances Data)

Upstream product

• 95-64-7 4-amino-o-xylene 
• 4318-56-3 3-methyl-6-chlorouracil 

Downstream Products

• 76896-51-0 10-(3,4-Dimethyl-phenyl)-3-methyl-10H-pyrimido[4,5-b]quinoline-2,4-dione 
• 76896-59-8 3,7,8-Trimethyl-5-phenyl-1H-pyrimido[4,5-b]quinoline-2,4-dione 
• 1079130-04-3 C₄₁H₅₅N₃O₂ 
• 84459-42-7 10-(3,4-Dimethyl-phenyl)-3-methyl-7-nitro-10H-pyrimido[4,5-b]quinoline-2,4-dione 
• 65626-86-0 10-(3,4-dimethyl-phenyl)-3-methyl-10H-benzo[g]pteridine-2,4-dione 
• 83983-33-9 6-(3,4-Dimethyl-anilino)-5-formyl-3-methyl-2,4(1H,3H)-pyrimidindion 
• 76896-40-7 C₃₃H₃₄N₆O₄ 
• 79177-60-9 10-(3,4-Dimethylphenyl)-3,7-dimethylpyrido<2,3-d:6,5-d'>pyrimidine 

Relevant articles and documents

Synthesis, biological active molecular design, and molecular docking study of novel deazaflavin-cholestane hybrid compounds

Novel deazaflavin-cholestane hybrid compounds, 3′,8′-disubstituted-5′-deazacholest-2,4-dieno[2,3-g]pteridine-2′,4′(3′H,8′H)-diones, have been synthesized by condensation reaction between 6-(monosubstituted amino)-pyrimidin-2,4(1H,3H)-diones and 2-hydroxymethylenecholest-4-en-3-one in presence of p-toluenesulfonic acid monohydrate and diphenyl ether. The antitumor activities against human tumor cell lines (CCRF-HSB-2 and KB cells) have been investigated in vitro, and many of these compounds showed promising antitumor activities. Furthermore, molecular docking study using LigandFit within the software package Discovery Studio 1.7 was done for lead optimization of these compounds as potential PTK inhibitors. In general, all of the synthesized steroid-hybrid compounds showed good binding affinities into PTK (PDB code: 1t46).

Flavins as potential antimalarials. 2. 3-Methyl-10-(substituted-phenyl)flavins

A series of 3-methyl-10-(substituted-phenyl)flavins was prepared and tested for antimalarial activity against the lethal parasite Plasmodium vinckei in mice. Several of these analogues were found to be effective antimalarial agents. A quantitative structure-activity relationship study was undertaken with 44 analogues and no satisfactory relationship could be established.