5980-02-9 Usage
General Description
Vindolinine is a natural product found in the leaves of the Madagascar periwinkle plant, Catharanthus roseus. It belongs to the class of chemical compounds known as indoles, and is a key intermediate in the biosynthetic pathway for the production of the anti-cancer drugs vinblastine and vincristine. Vindolinine has been the subject of extensive research due to its potential pharmacological properties, particularly as an anticancer agent. It has also been studied for its potential use in treating diabetes, as well as its antibacterial and antifungal properties. Vindolinine is a promising compound for further development of new drugs with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 5980-02-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,8 and 0 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5980-02:
(6*5)+(5*9)+(4*8)+(3*0)+(2*0)+(1*2)=109
109 % 10 = 9
So 5980-02-9 is a valid CAS Registry Number.
InChI:InChI=1/C21H24N2O2/c1-13-19-8-5-10-23-11-9-20(18(19)23)14-6-3-4-7-16(14)22-21(13,20)15(12-19)17(24)25-2/h3-8,13,15,18,22H,9-12H2,1-2H3
5980-02-9Relevant articles and documents
SYNTHESIS OF HEXACYCLIC INDOLE ALKALOIDS RELATED TO VINDOLININE BY SONOCHEMICAL CYCLIZATION
Hugel, Georgette,Cartier, Dominique,Levy, Jean
, p. 4513 - 4516 (2007/10/02)
Upon treatment with sodium in THF under sonication, 19-iodotabersonine underwent cyclization to the vindolinine ring system.The yields and ratio of the diastereomers thus obtained depended on the sonication parameters.
