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Vindolinine, a natural product derived from the leaves of the Madagascar periwinkle plant (Catharanthus roseus), is an indole alkaloid and a key intermediate in the biosynthesis of the anti-cancer drugs vinblastine and vincristine. It has garnered significant attention due to its potential pharmacological properties, particularly as an anticancer agent, and has been studied for its potential in treating diabetes, as well as its antibacterial and antifungal properties. Vindolinine is a promising compound for the development of new drugs with a range of therapeutic applications.

5980-02-9

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5980-02-9 Usage

Uses

Used in Pharmaceutical Industry:
Vindolinine is used as an intermediate in the production of anti-cancer drugs for its role in the biosynthetic pathway of vinblastine and vincristine, which are effective in treating various types of cancer.
Used in Anticancer Applications:
Vindolinine is employed as a potential anticancer agent, with ongoing research exploring its direct effects on cancer cells and its potential to enhance the efficacy of existing cancer treatments.
Used in Diabetes Treatment:
Vindolinine is used as a potential therapeutic agent in diabetes research, with studies investigating its ability to improve glycemic control and insulin sensitivity.
Used in Antibacterial and Antifungal Applications:
Vindolinine is used as a potential agent in the development of new antibiotics and antifungal medications, given its demonstrated antibacterial and antifungal properties, which could contribute to addressing the growing issue of drug-resistant infections.

Check Digit Verification of cas no

The CAS Registry Mumber 5980-02-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,8 and 0 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5980-02:
(6*5)+(5*9)+(4*8)+(3*0)+(2*0)+(1*2)=109
109 % 10 = 9
So 5980-02-9 is a valid CAS Registry Number.
InChI:InChI=1/C21H24N2O2/c1-13-19-8-5-10-23-11-9-20(18(19)23)14-6-3-4-7-16(14)22-21(13,20)15(12-19)17(24)25-2/h3-8,13,15,18,22H,9-12H2,1-2H3

5980-02-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Vindolinine

1.2 Other means of identification

Product number -
Other names (-)-Vindolinine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5980-02-9 SDS

5980-02-9Downstream Products

5980-02-9Relevant academic research and scientific papers

SYNTHESIS OF HEXACYCLIC INDOLE ALKALOIDS RELATED TO VINDOLININE BY SONOCHEMICAL CYCLIZATION

Hugel, Georgette,Cartier, Dominique,Levy, Jean

, p. 4513 - 4516 (2007/10/02)

Upon treatment with sodium in THF under sonication, 19-iodotabersonine underwent cyclization to the vindolinine ring system.The yields and ratio of the diastereomers thus obtained depended on the sonication parameters.

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