59801-62-6

Basic information

• Product Name: THIOMORPHOLINE 1,1-DIOXIDE HYDROCHLORIDE
• Synonyms: THIOMORPHOLINE 1,1-DIOXIDE HCL;THIOMORPHOLINE 1,1-DIOXIDE HYDROCHLORIDE;THIOMORPHOLINE-1,1-OXIDE HYDROCHLORIDE;Thiomorpholine-1,1-dioxide hydrochloride >90%;1,1-DIOXIDE-4-THIOMORPHOLINE HYDROCHLORIDE;Thiomorpholine dioxide hydrogen chloride;1$l^{6},4-thioMorpholine-1,1-dione hydrochloride;ThioMorpholine,1,1-dioxide, hydrochloride (1:1)
• CAS NO: 59801-62-6
• Molecular Formula: C₄H₉NO₂S*ClH
• Molecular Weight: 171.65
• Product Categories: Intermediate
• Mol File: 59801-62-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 307 °C (decomp)
• Boiling Point: 353.6 °C at 760 mmHg
• Flash Point: 167.6 °C
• Appearance: white to light yellow solid
• Vapor Pressure: 2.48E-05mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: THIOMORPHOLINE 1,1-DIOXIDE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: THIOMORPHOLINE 1,1-DIOXIDE HYDROCHLORIDE(59801-62-6)
• EPA Substance Registry System: THIOMORPHOLINE 1,1-DIOXIDE HYDROCHLORIDE(59801-62-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 59801-62-6(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow solid

InChI:InChI=1/C4H9NO2S.ClH/c6-8(7)3-1-5-2-4-8;/h5H,1-4H2;1H

Upstream product

• 25343-91-3 N-methylthiomorpholine 1,1-dioxide 
• 627-11-2 2-Chloroethyl chloroformate 
• 215791-95-0 tert-butyl thiomorpholine-4-carboxylic acid-1,1-dioxide 

Downstream Products

• 1206161-97-8 N-(5-{4-[(1,1-dioxo-1λ⁶-thiomorpholin-4-yl)methyl]phenyl}-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide 
• 1973485-27-6 4-(4-bromo-3-fluorobenzyl)-1,1-dioxo-1-thiomorpholine 
• 867333-26-4 (4-bromophenyl)(1,1-dioxo-1-thiomorpholino)methanone 
• 1092563-25-1 4-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-thiomorpholine-1,1-dioxide 
• 1249852-46-7 4-(3-bromobenzyl)thiomorpholine 1,1-dioxide 

Relevant articles and documents

PYRROLIDINE GLYCOSIDASE INHIBITORS

Compounds of formula (I) wherein A, W, R3b, Z and p have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.

AZAARENE DERIVATIVES

A compound represented by the general formula: wherein X1 represents a nitrogen atom or a group represented by the formula -CR10=; X2 represents a nitrogen atom or a group represented by the formula -CR11=; Y represents an oxygen atom or the like; R1 represents a C1-6 alkoxy group, an optionally substituted C6-10 aryloxy group, a group represented by the formula -NR12aR12b or the like; R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like; R3, R4, R5, R6, R7, R8, R10 and R11 each independently represent a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, or the like; R9 represents a group represented by the formula -NR16aR16b or the like; and R12a, R12b, R16a and R16b each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, a salt thereof, or a hydrate of the foregoing.

Quinoline and quinazoline compounds useful in therapy

Compounds of formula I, wherein R1 represents C1-4 alkoxy optionally substituted by one or more fluorine atoms; R2 represents an aryl group or a heteroaryl group, optionally substituted by C1-4 alkyl or SO2