59819-52-2

Basic information

• Product Name: (2-CHLOROPHENYL)(2,2,2-TRICHLOROETHYL) CHLOROPHOSPHATE
• Synonyms: 2,2,2-TRICHLOROETHYL ESTER;2,2,2-TRICHLOROETHYL-O-CHLOROPHENYLPHOSPHOCHLORIDATE;(2-CHLOROPHENYL)(2,2,2-TRICHLOROETHYL) CHLOROPHOSPHATE;CHLOROPHOSPHORIC ACID 2-CHLOROPHENYL;Phosphorochloridic acid, 2-chlorophenyl 2,2,2-trichloroethyl ester;Chloridophosphoric acid 2-chlorophenyl 2,2,2-trichloroethyl ester
• CAS NO: 59819-52-2
• Molecular Formula: C₈H₆Cl₅O₃P
• Molecular Weight: 358.37
• EINECS: 261-939-1
• Product Categories: Organic Building Blocks;Phosphorus Compounds;Phosphorus Halides
• Mol File: 59819-52-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 366.7°C at 760 mmHg
• Flash Point: 260.3°C
• Appearance: /
• Density: 1.574 g/mL at 20 °C(lit.)
• Vapor Pressure: 3.04E-05mmHg at 25°C
• Refractive Index: n20/D 1.535
• CAS DataBase Reference: (2-CHLOROPHENYL)(2,2,2-TRICHLOROETHYL) CHLOROPHOSPHATE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-CHLOROPHENYL)(2,2,2-TRICHLOROETHYL) CHLOROPHOSPHATE(59819-52-2)
• EPA Substance Registry System: (2-CHLOROPHENYL)(2,2,2-TRICHLOROETHYL) CHLOROPHOSPHATE(59819-52-2)

Safety Data

• Hazard Codes: C
• Statements: 14-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• F: 10-21
• HazardClass: 6.1(a)
• PackingGroup: II
• Hazardous Substances Data: 59819-52-2(Hazardous Substances Data)

Usage

Description

(2-CHLOROPHENYL)(2,2,2-TRICHLOROETHYL) CHLOROPHOSPHATE, commonly known as CHLORPHOS, is an organophosphate compound that functions as an insecticide and acaricide. It operates by inhibiting acetylcholinesterase, a critical enzyme for the nervous system's proper functioning in insects, leading to overstimulation, paralysis, and death of the targeted pests. Due to its high toxicity to both insects and mammals, CHLORPHOS requires careful handling and is classified as a restricted use pesticide by the Environmental Protection Agency to mitigate the risks of acute and chronic toxicity.
Used in Pest Control Industry:
CHLORPHOS is used as an insecticide and acaricide for controlling a variety of pests in agriculture and other settings. Its application is aimed at protecting crops and reducing damage caused by insects, thereby ensuring higher yields and better quality produce. Due to its high potency and effectiveness, it is a preferred choice in situations where pest infestations are severe or resistant to other treatments.
Used in Public Health:
In public health settings, CHLORPHOS is used for controlling disease-transmitting insects such as mosquitoes, ticks, and fleas. Its application helps in reducing the spread of vector-borne diseases, thus contributing to improved public health and well-being.
Used in Veterinary Medicine:
CHLORPHOS is also utilized in veterinary medicine for treating and preventing infestations in livestock and pets. Its application ensures the health and comfort of animals by eliminating parasites that can cause various health issues and discomfort.

InChI:InChI=1/C8H6Cl5O3P/c9-6-3-1-2-4-7(6)16-17(13,14)15-5-8(10,11)12/h1-4H,5H2

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Relevant articles and documents

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Enzymatic process for 3-substituted cephalosporins

6β-(3-Carboxyphenylacetylamino)-2α-substituted--2β-methylpenam-3-carboxylic acids and 6β-adipoylamino--2α-substituted-2β-methylpenam-3-carboxylic acids, wherein the α-substituent is C1-C3 alkyl, C1-C3 alkoxy, vinyl or allenyl, are converted by the enzyme deacetoxy-cephalosporin C synthetase to the 7β-(3-carboxyphenyl-acetylamino)-3-substituted-3-cephem-4-carboxylic acid and the 7β-adipoylamino-3-substituted-3-cephem-4-car-boxylic acid.