59843-55-9

Usage

Uses

Used in Pharmaceutical Applications:
3-(2-Chloro-phenyl)-1h-pyrazole is used as a pharmaceutical agent for its anti-inflammatory properties, which can help in the treatment of various inflammatory conditions. Its anti-tumor activities also make it a promising candidate for cancer therapy, where it may contribute to the inhibition of tumor growth and progression.
Used in Agrochemical Applications:
In the agrochemical industry, 3-(2-Chloro-phenyl)-1h-pyrazole is utilized for its potential to control pests and diseases in crops, thereby enhancing agricultural productivity and crop protection.
Used in Organic Synthesis:
3-(2-Chloro-phenyl)-1h-pyrazole serves as a building block in the synthesis of other organic compounds, contributing to the development of new chemical entities with diverse applications in various industries, including pharmaceuticals, materials science, and specialty chemicals.
Researchers in the fields of medicinal chemistry, biochemistry, and organic synthesis are actively exploring the potential of 3-(2-Chloro-phenyl)-1h-pyrazole due to its diverse biological activities and wide-ranging applications.

InChI:InChI=1/C9H7ClN2/c10-8-4-2-1-3-7(8)9-5-6-11-12-9/h1-6H,(H,11,12)

Upstream product

• 903550-31-2 5-(2-chloro-phenyl)-1-(tetrahydro-pyran-2-yl)-1H-pyrazole 
• 844501-71-9 3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole 
• 615-41-8 2-iodochlorobenzene 

Downstream Products

• 149739-70-8 4-bromo-3-(2-chlorophenyl)-1H-pyrazole 
• 59843-57-1 2-[5-(2-chloro-phenyl)-pyrazol-1-yl]-N,N-dimethyl-propionamide 
• 59843-56-0 2-[3-(2-chloro-phenyl)-pyrazol-1-yl]-N,N-dimethyl-propionamide 
• 59844-07-4 2-[3-(2-chloro-phenyl)-pyrazol-1-yl]-N,N-dimethyl-butyramide 
• 1332506-36-1 2-(o-chlorophenyl)-6-ethoxycarbonyl-7-methylpyrazolo[1,5-a]pyrimidine 
• 1415012-53-1 [Ag(μ-3-(o-Cl-C₆H₄)pz)]₃ 
• 1445891-10-0 N-(4-(4-bromo-3-(2-chlorophenyl)-1H-pyrazol-1-yl)-5-methylpyridin-2-yl)acetamide 
• 1445889-83-7 N-{4-[4-(6-aminopyridin-2-yl)-3-(2-chlorophenyl)-1H-pyrazol-1-yl]-5-methylpyridin-2-yl}acetamide 
• 1335210-77-9 C₁₉H₁₅ClN₂O₂ 
• 1335210-52-0 C₂₃H₁₅ClN₂ 

Relevant academic research and scientific papers

HETEROARYLS AND USES THEREOF

This invention provides compounds of formula IB: and also provides compounds of formulas ID, IIB, VB, and IIC: wherein HY, R1, R2, G5, G6, G7, G8, and G9 are as described in the specification. The compounds are inhibitors of VPS34 and/or PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

Efficient and simple synthesis of 3-aryl-1H-pyrazoles

Efficient preparation of 3-aryl-1H-pyrazoles by reaction of 1-protected-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoles with (het)aryl halides is described. The choice of THP protecting group is discussed.