59878-57-8Relevant articles and documents
Benzofuran derivative as well as preparation method and medical application thereof
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Paragraph 0254-0257; 0277-0280, (2020/07/15)
The invention relates to benzofuran derivatives, and a preparation method and medical application thereof. Specifically, the present invention relates to a new benzofuran derivative represented by general formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, and application of the composition as a therapeutic agent, especially as a PAR-4 antagonist, wherein each substituent of general formula (I) is as defined in the specification.
POLY (ADP-RIBOSE) POLYMERASE INHIBITOR
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Paragraph 0094, (2014/11/13)
Disclosed are a phthalic hydrazide (phthalazine ketone) compound, and a pharmaceutical composition comprising the same. As a DNA repair enzyme poly (ADP-ribozyme) polymerase inhibitor, the compound and the pharmaceutical composition can effectively treat diseases involving PARP enzymatic activity, including cancer, neural degenerative diseases, inflammation and the like.
PYRROLO[2,1-F] [1,2,4] TRIAZIN-4-YLAMINES IGF-1R KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER HYPERPROLIFERATIVE DISEASES
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Page/Page column 103, (2010/11/27)
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