5988-76-1 Usage
General Description
Cucurbitacin C is a potent natural compound that can be found in various plant species from the Cucurbitaceae family including cucumbers, melons, and pumpkins. It is known for its bitter taste and has been identified as toxic in large amounts. Traditional medical practitioners have recommended it for its potential health benefits thanks to its anti-inflammatory and anticancer properties. Moreover, scientific research has shown that Cucurbitacin C can indeed obstruct the growth of certain cancer cells and reduce inflammation. Despite its potential medicinal properties, its toxicity means it should be used cautiously and under professional supervision.
Check Digit Verification of cas no
The CAS Registry Mumber 5988-76-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,8 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5988-76:
(6*5)+(5*9)+(4*8)+(3*8)+(2*7)+(1*6)=151
151 % 10 = 1
So 5988-76-1 is a valid CAS Registry Number.
InChI:InChI=1/C32H48O8/c1-18(34)40-27(2,3)14-13-24(37)31(8,39)26-21(35)15-29(6)22-11-9-19-20(10-12-23(36)28(19,4)5)32(22,17-33)25(38)16-30(26,29)7/h9,13-14,20-23,26,33,35-36,39H,10-12,15-17H2,1-8H3/b14-13+/t20-,21-,22?,23+,26?,29?,30?,31?,32?/m1/s1
5988-76-1Relevant articles and documents
Biosynthesis, regulation, and domestication of bitterness in cucumber
Shang, Yi,Ma, Yongshuo,Zhou, Yuan,Zhang, Huimin,Duan, Lixin,Chen, Huiming,Zeng, Jianguo,Zhou, Qian,Wang, Shenhao,Gu, Wenjia,Liu, Min,Ren, Jinwei,Gu, Xingfang,Zhang, Shengping,Wang, Ye,Yasukawa, Ken,Bouwmeester, Harro J.,Qi, Xiaoquan,Zhang, Zhonghua,Lucas, William J.,Huang, Sanwen
, p. 1084 - 1088 (2015/02/19)
Cucurbitacins are triterpenoids that confer a bitter taste in cucurbits such as cucumber, melon, watermelon, squash, and pumpkin. These compounds discourage most pests on the plant and have also been shown to have antitumor properties. With genomics and biochemistry, we identified nine cucumber genes in the pathway for biosynthesis of cucurbitacin C and elucidated four catalytic steps.We discovered transcription factors Bl ( Bitter leaf) and Bt (Bitter fruit) that regulate this pathway in leaves and fruits, respectively. Traces in genomic signatures indicated that selection imposed on Bt during domestication led to derivation of nonbitter cucurbits from their bitter ancestors.
