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Cucurbitacin C is a potent natural compound derived from various plant species within the Cucurbitaceae family, such as cucumbers, melons, and pumpkins. It is characterized by its bitter taste and recognized for its potential health benefits, despite being toxic in large quantities. Traditional medical practitioners have long advocated for its use due to its anti-inflammatory and anticancer properties, which have been supported by scientific research demonstrating its ability to inhibit the growth of certain cancer cells and reduce inflammation. However, due to its toxicity, Cucurbitacin C should be used with caution and under professional guidance.

5988-76-1

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5988-76-1 Usage

Uses

Used in Pharmaceutical Applications:
Cucurbitacin C is used as an anticancer agent for its potential to obstruct the growth of certain cancer cells. It is particularly effective in targeting and inhibiting the proliferation of cancerous cells, making it a valuable compound in the development of cancer treatments.
Used in Anti-inflammatory Applications:
Cucurbitacin C is used as an anti-inflammatory agent, leveraging its ability to reduce inflammation and alleviate symptoms associated with inflammatory conditions. This property makes it a promising candidate for the treatment of various inflammatory diseases.
Used in Traditional Medicine:
Cucurbitacin C is used as a therapeutic agent in traditional medicine practices, where it is valued for its potential health benefits. Its use in these practices is based on historical knowledge and anecdotal evidence, although modern scientific research is increasingly validating these traditional uses.
Used in Research and Development:
Cucurbitacin C is used as a research compound in the development of new pharmaceuticals and therapeutic strategies. Its unique properties and potential applications make it an important substance for scientific investigation, with the aim of uncovering new ways to harness its benefits while mitigating its toxic effects.
Used in Drug Delivery Systems:
Cucurbitacin C is used in the development of drug delivery systems to improve its bioavailability and therapeutic outcomes. By incorporating Cucurbitacin C into various carriers, such as organic and metallic nanoparticles, researchers aim to enhance its delivery to target tissues and cells, thereby increasing its efficacy and reducing potential side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 5988-76-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,8 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5988-76:
(6*5)+(5*9)+(4*8)+(3*8)+(2*7)+(1*6)=151
151 % 10 = 1
So 5988-76-1 is a valid CAS Registry Number.
InChI:InChI=1/C32H48O8/c1-18(34)40-27(2,3)14-13-24(37)31(8,39)26-21(35)15-29(6)22-11-9-19-20(10-12-23(36)28(19,4)5)32(22,17-33)25(38)16-30(26,29)7/h9,13-14,20-23,26,33,35-36,39H,10-12,15-17H2,1-8H3/b14-13+/t20-,21-,22?,23+,26?,29?,30?,31?,32?/m1/s1

5988-76-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name [(E,6R)-6-[(3S,8S,9R,10R,13R,14S,16R,17R)-3,16-dihydroxy-9-(hydroxymethyl)-4,4,13,14-tetramethyl-11-oxo-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate

1.2 Other means of identification

Product number -
Other names CUCURBITACIN C

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5988-76-1 SDS

5988-76-1Upstream product

5988-76-1Downstream Products

5988-76-1Relevant academic research and scientific papers

Biosynthesis, regulation, and domestication of bitterness in cucumber

Shang, Yi,Ma, Yongshuo,Zhou, Yuan,Zhang, Huimin,Duan, Lixin,Chen, Huiming,Zeng, Jianguo,Zhou, Qian,Wang, Shenhao,Gu, Wenjia,Liu, Min,Ren, Jinwei,Gu, Xingfang,Zhang, Shengping,Wang, Ye,Yasukawa, Ken,Bouwmeester, Harro J.,Qi, Xiaoquan,Zhang, Zhonghua,Lucas, William J.,Huang, Sanwen

, p. 1084 - 1088 (2015/02/19)

Cucurbitacins are triterpenoids that confer a bitter taste in cucurbits such as cucumber, melon, watermelon, squash, and pumpkin. These compounds discourage most pests on the plant and have also been shown to have antitumor properties. With genomics and biochemistry, we identified nine cucumber genes in the pathway for biosynthesis of cucurbitacin C and elucidated four catalytic steps.We discovered transcription factors Bl ( Bitter leaf) and Bt (Bitter fruit) that regulate this pathway in leaves and fruits, respectively. Traces in genomic signatures indicated that selection imposed on Bt during domestication led to derivation of nonbitter cucurbits from their bitter ancestors.

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