59886-41-8 Usage
Chemical structure
2,5-bis(aziridin-1-yl)-3,6-di(morpholin-4-yl)cyclohexa-2,5-diene-1,4-dione is a complex organic compound consisting of a cyclohexadiene ring with aziridine and morpholine functional groups attached.
Antineoplastic and antitumor properties
2,5-bis(aziridin-1-yl)-3,6-di(morpholin-4-yl)cyclohexa-2,5-diene-1,4-dione has the potential to inhibit the growth and spread of cancer cells, making it a candidate for cancer treatment.
Bismustard compound
It contains both aziridine and morpholine functional groups, which contribute to its antineoplastic properties.
DNA crosslinking ability
The compound has been studied for its ability to crosslink DNA, which can interfere with the replication and transcription processes of cancer cells, ultimately inhibiting their growth.
Inhibition of cancer cell growth
2,5-bis(aziridin-1-yl)-3,6-di(morpholin-4-yl)cyclohexa-2,5-diene-1,4-dione has shown promise in preclinical studies in inhibiting the growth of various types of cancer cells.
Potential therapeutic applications
Due to its antineoplastic and antitumor properties, 2,5-bis(aziridin-1-yl)-3,6-di(morpholin-4-yl)cyclohexa-2,5-diene-1,4-dione may be useful in the treatment of various types of cancer.
Need for further research
Although the compound has shown promise in preclinical studies, more research is needed to fully understand its mechanism of action and potential therapeutic applications in cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 59886-41-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,8,8 and 6 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 59886-41:
(7*5)+(6*9)+(5*8)+(4*8)+(3*6)+(2*4)+(1*1)=188
188 % 10 = 8
So 59886-41-8 is a valid CAS Registry Number.
59886-41-8Relevant academic research and scientific papers
Potential central nervous system antitumor agents. Aziridinylbenzoquinones. 2
Chou,Khan,Driscoll
, p. 1302 - 1308 (2007/10/09)
A series of 15 2,5 diaziridinyl 3,6 bis(alkylamino) 1,4 benzoquinone derivatives was synthesized and evaluated as central nervous system antitumor agents in the murine intracerebral L1210 and ependymoblastoma brain tumor systems. Intraperitoneal activity was evaluated in the leukemia L1210, P388, and B16 melanocarcinoma tumor models. The more hydrophilic hydroxyalkylamino compounds were the most effective in the intraperitoneal ascites systems (L1210, P388) with the dihydroxypropylamino and hydroxyethylamino analogues producing long term survivors. The simple, more lipophilic mono and dialkylamino derivatives were most effective in the intracerebral systems. Multiple long term survivors were obtained with the methyl, ethyl, and dimethylamino compounds in the ependymoblastoma brain tumor system. The parent amino analogue was very active in several tumor models. The relationships between structure, activity, and water solubility are discussed.
