59898-69-0

Usage

InChI:InChI=1/C17H16N2OS2/c1-10-6-8-11(9-7-10)19-16(20)14-12-4-2-3-5-13(12)22-15(14)18-17(19)21/h6-9H,2-5H2,1H3,(H,18,21)

Upstream product

• 59898-55-4 N¹-(3-carbethoxy-4,5,6,7-tetrahydrobenzothien-2-yl)-N²-p-tolylthiourea 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 622-59-3 1-isothiocyanato-4-methylbenzene 
• 126105-68-8 4-imino-2-thioxo-1,2,5,6,7,8-tetrahydro-4H-benzothieno<2,3-d><1,3>thiazine 
• 4651-91-6 3-cyano-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene 
• 13037-22-4 methyl (N-(4-methylphenyl))dithiocarbamate 

Downstream Products

• 59898-77-0 (4-oxo-3-p-tolyl-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-acetic acid 
• 59898-83-8 (4-oxo-3-p-tolyl-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-acetic acid ethyl ester 

Relevant academic research and scientific papers

Structure-activity relationship analysis of a novel necroptosis inhibitor, Necrostatin-5

Necrostatin-5 (Nec-5) is a novel potent small-molecule inhibitor of necroptosis structurally distinct from previously described Necrostatin-1 (Nec-1), and therefore, represents a new direction for the inhibition of this cellular caspase-independent necrot

Interaction of heterothiocumulenes with 2-amino-3-cyanothiophenes: Formation of thienopyrimidines

Thieno-fused(1,3)-thiazine, 4-imino-2-thioxo-2,4-dihydro-1H-thieno(1,3)-thiazine (2) has been directly synthesised by the reaction of o-aminonitrile (1a) with carbon disulphide.Thiazine (2) on reaction with primary aromatic amines leads to thieno2

METHYL N-ARYLDITHIOCARBAMATES: USEFUL REAGENTS FOR THE ANNELATION OF PYRIMIDINES AND 1,3-OXAZINES TO FIVE-MEMBERED HETEROCYCLIC RINGS

The reaction of methyl N-aryldithiocarbamates with ?-excessive heteroaromatic o-amino acid derivatives leads to the annelation of 4-oxo-2-thioxopyrimidines, 2,4-dioxopyrimidines or 2-arylamino-1,3-oxazines, depending on the reaction conditions.

Synthesis of 3 substituted thieno[2,3 d]pyrimidin 4(3H) one 2 mercaptoacetic acids and their ethyl esters for pharmacological screening

3 Substituted thieno[2,3 d]pyrimidin 4(3H) one 2 mercaptoacetic acids and their ethyl esters were synthesized from 2 mercaptothieno[2,3 d]pyrimidin 4 (3H) ones, which were obtained by cyclization of thienylthioureas in acidic medium. Analgesic, anti inflammatory, and anticonvulsant activities were found in some of these compounds. Significant antimicrobial activity was exhibited by thienylthioureas.