59907-13-0

Basic information

• Product Name: 2-BROMO-3-FLUOROTOLUENE
• Synonyms: 2-BROMO-3-FLUOROTOLUENE;3-Fluoro-2-Bromo Toluene;2-Bromo-1-fluoro-3-methylbenzene;2-Bromo-3-fuluorotoluene;2-bromo-1-fluoro-3-methyl-
• CAS NO: 59907-13-0
• Molecular Formula: C₇H₆BrF
• Molecular Weight: 189.02
• EINECS: 261-982-6
• Product Categories: Fluorin-contained toluene series;Halogen toluene;Pyridines
• Mol File: 59907-13-0.mol

Chemical Properties

• Melting Point: 118-123℃
• Boiling Point: 187°C
• Flash Point: 76°(169°F)
• Appearance: /
• Density: 1.503
• Vapor Pressure: 1.09mmHg at 25°C
• Refractive Index: 1.5330
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 2-BROMO-3-FLUOROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-3-FLUOROTOLUENE(59907-13-0)
• EPA Substance Registry System: 2-BROMO-3-FLUOROTOLUENE(59907-13-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 59907-13-0(Hazardous Substances Data)

Usage

Uses

Used in Agrochemical Industry:
2-Bromo-3-fluorotoluene is used as a key intermediate in the synthesis of agrochemicals for its ability to contribute to the development of novel and effective pesticides and herbicides. Its unique structure allows for the creation of compounds with specific target pest profiles, enhancing crop protection and yield.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-bromo-3-fluorotoluene serves as a crucial building block for the synthesis of various drug molecules. Its presence in the molecular structure can influence the pharmacokinetics, pharmacodynamics, and overall efficacy of the resulting pharmaceutical compounds, making it an essential component in drug discovery and development.
Used in Dye Industry:
2-Bromo-3-fluorotoluene is utilized as a vital intermediate in the production of dyes and pigments due to its ability to impart specific color characteristics and properties to the final product. Its unique structure allows for the creation of dyes with improved colorfastness, stability, and application versatility in various industries such as textiles, plastics, and printing inks.

InChI:InChI=1/C7H6BrF/c1-5-3-2-4-6(9)7(5)8/h2-4H,1H3

Upstream product

• 54879-20-8 2-bromo-3-methylaniline 

Downstream Products

• 77971-10-9 (1R,8S)-3,11,11-Trimethyl-1,8-diphenyl-11-sila-tricyclo[6.2.1.0^2,7]undeca-2⁽⁷⁾,3,5,9-tetraene 
• 77971-15-4 (1R,8S)-3,11,11-Trimethyl-1,8,9,10-tetraphenyl-11-sila-tricyclo[6.2.1.0^2,7]undeca-2⁽⁷⁾,3,5,9-tetraene 
• 1123175-97-2 N-benzyl-1-methyl-9,10-dihydroanthracene-9,10-imine hydrochloride 
• 1123175-96-1 N-benzyl-1-methyl-9,10-dihydroanthracene-9,10-imine 
• 1175689-29-8 4-(2-fluoro-6-methyl-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester 
• 1373223-13-2 3-bromo-2-fluoro-4-methylbenzaldehyde 

Relevant articles and documents

AZABENZOXAZOLES FOR THE TREATMENT OF CNS DISORDERS

The present invention relates to a7 nicotinic receptor agonists of formula (la) or (lb) as described herein and to a method for treating disorders of the Central Nervous System (CNS) and other disorders in a mammal, including a human, by administering to the mammal an a7 nicotinic receptor agonist of formula (la) or (lb). It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier and a CNS-penetrant a7nicotinic receptor agonist of formula (la) or (lb).