59908-53-1

Basic information

• Product Name: 1H-Indole-2-carboxylic acid, 5-chloro-1-Methyl-, ethyl ester
• Synonyms: 1H-Indole-2-carboxylic acid, 5-chloro-1-Methyl-, ethyl ester;Ethyl 5-chloro-1-Methyl-1H-indole-2-carboxylate
• CAS NO: 59908-53-1
• Molecular Formula: C₁₂H₁₂ClNO₂
• Molecular Weight: 237.68218
• Mol File: 59908-53-1.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Indole-2-carboxylic acid, 5-chloro-1-Methyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxylic acid, 5-chloro-1-Methyl-, ethyl ester(59908-53-1)
• EPA Substance Registry System: 1H-Indole-2-carboxylic acid, 5-chloro-1-Methyl-, ethyl ester(59908-53-1)

Safety Data

• Hazardous Substances Data: 59908-53-1(Hazardous Substances Data)

Usage

Molecular Weight

229.67 g/mol

Structure

A bicyclic indole ring system with a carboxylic acid group at position 2, a chlorine atom at position 5, a methyl group at position 1, and an ethyl ester group attached to the carboxylic acid.

Physical Properties

The physical properties of 1H-Indole-2-carboxylic acid, 5-chloro-1-Methyl-, ethyl ester are not specified in the material provided.

Applications

Potential applications in the pharmaceutical industry for therapeutic purposes, but specific uses and effects are still being investigated.

Importance

Valuable compound for further research and exploration in the field of medicinal chemistry due to its chemical structure and properties.

Upstream product

• 4792-67-0 5-chloro-indole-2-carboxylic acid ethyl ester 
• 74-88-4 methyl iodide 
• 74-83-9 methyl bromide 
• 5296-86-6 2-[(4-chlorophenyl)-hydrazono]-propionic acid ethyl ester 
• 106-47-8 4-chloro-aniline 
• 80-48-8 methyl p-toluene sulfonate 

Downstream Products

• 1620064-73-4 C₂₄H₂₁ClNO₃P 
• 1620065-09-9 C₂₈H₃₅ClNO₄P 
• 883529-71-3 5-chloro-1-methyl-1H-indole-2-carbaldehyde 

Relevant articles and documents

Divergent gold-catalysed reactions of cyclopropenylmethyl sulfonamides with tethered heteroaromatics

Cyclopropenylmethyl sulfonamides with tethered heteroaromatics have been demonstrated to undergo divergent gold-catalysed cyclisation reactions. A formal dearomative (4+3) cycloaddition takes place with furan-tethered substrates, yielding densely functionalised 5,7-fused heterocycles related to the bioactive curcusone natural products. Indole-tethered substrates display divergent reactivity giving biologically important tetrahydro-β-carbolines via a Friedel-Crafts mechanism.

Cycloaddition of in Situ Formed Azaoxyallyl Cations with 2-Alkenylindoles: An Approach to Tetrahydro-β-carbolinones

A novel [3 + 3] cycloaddition between in situ formed azaoxyallyl cations and 2-alkenylindoles has been developed. This concise method allows the efficient construction of a series of tetrahydro-β-carbolinones in good yields under mild conditions. Gram-sca

1H-pyrido[3,4-b]indole-4-carboxamide derivatives, preparation and application thereof in therapeutics

PCT No. PCT/FR97/01750 Sec. 371 Date Apr. 7, 1999 Sec. 102(e) Date Apr. 7, 1999 PCT Filed Oct. 8, 1997 PCT Pub. No. WO98/15552 PCT Pub. Date Apr. 16, 1998Compounds of general formula (I) in which the variables are as defined in the specification, their pr