599151-16-3

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 
• 552-89-6 2-nitro-benzaldehyde 
• 84465-82-7 tetrahydro-3,4,5,6-dimethyl-6,6-pyrannedione-2,4 

Relevant academic research and scientific papers

ZrOCl2 · 8H2O: An efficient, ecofriendly, and recyclable catalyst for ultrasound-accelerated, one-pot, solvent-free synthesis of 8-aryl-7,8-dihydro-[1,3]dioxolo[4,5-g] quinolin-6-(5H)-one and 4-aryl-3,4-dihydroquinolin-2(1 H)-one derivatives

A convenient, one-pot, solvent-free reaction of amines, aromatic aldehydes, and Meldrum's acid to form 8-aryl-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6- (5H)-one and 4-aryl-3,4-dihydroquinolin-2-(1H)-one in the presence of 10 mol% ZrOCl2 · 8H2O under ultrasonic irradiation is described. This new protocol offers several advantages including low catalyst loading, clean reaction, easy workup, use of recyclable and ecofriendly catalyst, short reaction times, good yields, and solvent-free conditions. Copyright

Ultrasound-promoted one-pot synthesis of 8-aryl-7,8-dihydro-[1,3]- dioxolo[4,5-g]quinolin-6(5H)-one derivatives under catalyst-free and solvent-free conditions

An ultrasound-accelerated one-pot procedure has been explored for the synthesis of 8-aryl-7,8-dihydro-[1,3]-dioxolo[4,5-g]quinolin-6(5H)-one derivatives using the reaction between 3,4-methylendioxyaniline 1, aldehyde 2 and isopropylidene malonate 3 under catalyst-free and solvent-free conditions. High yields of the products, mild reaction condition, environmentally friendly procedure, catalyst- and solvent-free conditions are the main advantages of this protocol.