59919-12-9

Upstream product

• 72653-47-5 α-chlorobutyl phenyl sulfide 
• 98-88-4 benzoyl chloride 
• 108-98-5 thiophenol 
• 49851-31-2 α-bromovalerophenone 
• 931-59-9 benzenesulfenyl chloride 
• 1009-14-9 phenyl butyl ketone 

Downstream Products

• 95607-26-4 1-phenyl-2-phenylsulphinylpentan-1-one 
• 109328-60-1 (E)-1-phenyl-2-phenylthiopent-3-en-1-on 
• 109328-59-8 (E)-2-methyl-1-phenyl-2-phenylthiopent-3-en-1-one 
• 95607-29-7 1-phenyl-2-phenylthiopent-2-en-1-one 
• 109328-52-1 (E)-1-phenyl-2-phenylthiopent-2-en-1-one 
• 98793-56-7 (Z)-1-phenyl-2-phenylthiopent-2en-1-one 

Relevant academic research and scientific papers

Copper-catalyzed cross-coupling reaction of α-sulfur-substituted alkylstannanes with acid chlorides

Copper compounds were found to catalyze the cross-coupling reaction of α-sulfur-substituted alkylstannanes with acid chlorides. Under the optimized conditions (CuF2 (1 mol %), 1,4-dioxane, 102 C), various substrates coupled to afford the corres

A convenient, catalyst-free cross-coupling reaction of α-sulfur- substituted alkylstannanes with acid chlorides leading to α-sulfur- substituted ketones

A thermal cross-coupling reaction of α-sulfur-substituted alkylstannanes with acid chlorides is described. A range of substrates can be used for the present reaction and the reaction proceeds by just mixing two components under reflux in mesitylene to giv

Preparation and reactivity of polyfunctional zinc and copper organometallics bearing sulfur functionalities

Iodomethylthiobenzoate 5 and α-chloroalkyl phenyl sulfides 6 were found to insert zinc dust in THF under very mild conditions (10-25°C, 0.5-2 h) leading to zinc α-thioorganometallics. After a transmetallation with CuCN·2 LiCl, the corresponding copper rea

Preparation of Functionalized Zinc and Copper Organometallics Containing Sulfur Functionalities at the Alpha or Gamma Position

α-Chloroalkyl phenyl sulfides 1 readily insert zinc in THF at 25 deg C (0.5-2 h), affording sulfur stabilized organozinc derivatives of type 2.The presence of a functional group such as an ester or a cyano group is tolerated in these organometallics.After a transmetallation to the corresponding copper reagent 3, they react with a wide range of electrophiles.Zinc and copper organometallics bearing a thiophenyl or a phenylsulfinyl group at the γ-position have also been prepared showing the generality of our approach.

Synthesis of α-Phenylthio Enones and Esters of α-Phenylthio Alkenoic Acids

The title compounds can be made by a Pummerer dehydration from the corresponding saturated sulphoxides.The alkylation of anions from saturated and unsaturated ketones is described.