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599202-49-0

Benzenamine, 4-ethoxy-3-(5-phenyl-2-benzoxazolyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 599202-49-0 Structure

  • Basic information

    1. Product Name: Benzenamine, 4-ethoxy-3-(5-phenyl-2-benzoxazolyl)-
    2. Synonyms:
    3. CAS NO:599202-49-0
    4. Molecular Formula: C21H18N2O2
    5. Molecular Weight: 330.386
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 599202-49-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Benzenamine, 4-ethoxy-3-(5-phenyl-2-benzoxazolyl)-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Benzenamine, 4-ethoxy-3-(5-phenyl-2-benzoxazolyl)-(599202-49-0)
    11. EPA Substance Registry System: Benzenamine, 4-ethoxy-3-(5-phenyl-2-benzoxazolyl)-(599202-49-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 599202-49-0(Hazardous Substances Data)

599202-49-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 599202-49-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,9,2,0 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 599202-49:
(8*5)+(7*9)+(6*9)+(5*2)+(4*0)+(3*2)+(2*4)+(1*9)=190
190 % 10 = 0
So 599202-49-0 is a valid CAS Registry Number.

599202-49-0Downstream Products

599202-49-0Relevant articles and documents

2,3-Dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acid derivatives: A novel class of small molecule heparanase inhibitors

Courtney, Stephen M.,Hay, Philip A.,Buck, Richard T.,Colville, Claire S.,Porter, David W.,Scopes, David I. C.,Pollard, Faye C.,Page, Martin J.,Bennett, James M.,Hircock, Margaret L.,McKenzie, Edward A.,Stubberfield, Colin R.,Turner, Paul R.

, p. 3269 - 3273 (2007/10/03)

A novel class of 2,3-dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acids are described as inhibitors of the endo-β-glucuronidase heparanase. Several of the compounds, for example, 2-[4-propylamino-5-[5-(4-chloro)phenyl-benzoxazol-2- yl]phenyl]-2,3-dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acid (9c), display potent heparanase inhibitory activity (IC50 200-500nM) and have high selectivity (>100-fold) over human β-glucuronidase. They also show anti-angiogenic effects. Such compounds should serve as useful biological tools and may provide a basis for the design of novel therapeutic agents.

PHTHALIMIDE CARBOXYLIC ACID DERIVATIVES

-

Page/Page column 41, (2008/06/13)

The present invention relates to phthalimide carboxylic acid derivatives of formula (I), methods for their preparation, pharmaceutical compositions containing them and their use in medicine, specifically in the treatment of cancer. (I), wherein X is O or S; R1 is a phthalimide carboxylic acid group of formula (II). R is hydrogen, C1-C6 alkyl, aryl or C1-C3 alkylaryl and R2, R3 and R4 represent various substituents.

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