59939-74-1 Usage
General Description
Piperazin-1-yl-thiophen-3-yl-methanone is a chemical compound with the molecular formula C12H14N2OS. It consists of a piperazine ring, a thiophene ring, and a methanone group. It is commonly used in medicinal chemistry for the synthesis of pharmaceuticals and drug candidates. The compound has potential applications in the treatment of various medical conditions due to its ability to interact with biological targets in the body. Additionally, it has been studied for its role as an antipsychotic and anxiolytic agent. Overall, piperazin-1-yl-thiophen-3-yl-methanone has important implications in the field of drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 59939-74-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,9,3 and 9 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 59939-74:
(7*5)+(6*9)+(5*9)+(4*3)+(3*9)+(2*7)+(1*4)=191
191 % 10 = 1
So 59939-74-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H12N2OS/c12-9(8-1-6-13-7-8)11-4-2-10-3-5-11/h1,6-7,10H,2-5H2
59939-74-1Relevant articles and documents
Efficient monoacylation of symmetrical secondary alkanediamines and synthesis of unsymmetrical diacylated alkanediamines. A new L-proline-based organocatalyst
Moulat, Laure,Martinez, Jean,Salom-Roig, Xavier J.
, p. 336 - 349 (2020/02/13)
A simple procedure was developed for the monoacylation of several unprotected alkanediamines with carboxylic acids by using PyBOP-HOBt as coupling agent in the presence of DIEA at room temperature. Yields were moderate with primary alkanediamines and good to excellent with linear or cyclic secondary ones. To illustrate the utility of these monoacylated products, six unsymmetrical diacylated alkanediamines were synthesized. In addition, one of these compounds was evaluated as organocatalyst in an asymmetric aldol reaction. R' R' NHR O R N O R N PyBOP, HOBt PyBOP, HOBt DIEA, DMF DIEA, DMF NHR NHR O N O 10 equiv O R 11 exemples R' R = H, alkyl R'' OH 67-95% yield R'' OH 6 exemples
