59964-94-2

Usage

Uses

Used in Pharmaceutical Industry:
BIPHENYL-2-YL-HYDRAZINE is used as an intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and medications. Its role in this industry is crucial for the production of a range of therapeutic agents.
Used in Dye Industry:
In the dye industry, BIPHENYL-2-YL-HYDRAZINE is utilized as an intermediate in the production of dyes, playing a significant part in the creation of colorants for textiles, plastics, and other materials.
Used in Organic Synthesis:
BIPHENYL-2-YL-HYDRAZINE is used as a building block in the synthesis of other organic compounds, facilitating the creation of a variety of chemical products that serve different purposes across various industries.
Used as a Reagent in Chemical Reactions:
BIPHENYL-2-YL-HYDRAZINE also serves as a reagent in numerous chemical reactions, aiding in the transformation of starting materials into desired products, which can be essential for research and industrial applications.

Upstream product

• 90-41-5 2-phenylaniline 
• 52500-12-6 biphenyl-2-diazonium ; chloride 
• 2051-60-7 2-chloro-1,1'-biphenyl 

Downstream Products

• 75600-96-3 ethyl (4-methoxyphenyl)glyoxylate 2-phenylphenylhydrazone 
• 149877-65-6 N'-Biphenyl-2-yl-hydrazinecarboxylic acid cyclopentyl ester 
• 1246200-12-3 ethyl 1-(biphenyl-2-yl)-5-methylpyrazole-3-carboxylate 
• 84-15-1 o-terphenyl 
• 230-17-1 benzo[c]cinnoline 

Relevant academic research and scientific papers

Palladium-catalyzed cross-coupling of aryl chlorides and tosylates with hydrazine

Hydrazine is not a problem anymore: The title transformation is the first reaction to yield aryl hydrazines through the cross-coupling of aryl chlorides and tosylates with hydrazine. An appropriately designed palladium catalyst allows this reaction to proceed rapidly under mild conditions, and with excellent chemoselectivity (see scheme; Ad=adamantyl, Ts=4-toluenesulfonyl).

Synthesis and Miticidal Activity of o-Biphenyldiazenecarboxylates

Nine o-biphenyldiazenecarboxylates were obtained in excellent yields by the air oxidation of o-biphenylhydrazinecarboxylates, catalyzed by palladium on charcoal.The miticidal activity of the new compounds was evaluated against Tetranychus urticae.Structure-activity relationships for the screened compounds are discussed.Some of the compounds displayed greater activity than did the commercial miticide propargite. Keywords: Miticides; o-biphenyldiazenecarboxylates; Tetranychus urticae

Antiimplantation Agents: Part I - 1-Arylthiosemicarbazides

Several 1-arylthiosemicarbazides, 2-arylhydrazinothiazolines and 2-arylhydrazinodihydrothiazines have been examined for their antiimplantation activity in rats.Among the active compounds, 4-methyl-1-(3,5-bistrifluoromethylphenyl)thiosemicarbazide (3, C 2696-Go) and the corresponding 4,4-dimethyl (47), ethyl (4), n-butyl (5) and allyl (6) derivatives completely inhibit implantation at doses 10, 3, 20, 20 and 30 mg/kg respectively.The 3,4-dichlorophenyl analogue (32) is effective at a dose of 30 mg/kg. 2-(3,5-Bistrifluoromethylphenyl)hydrazinothiazoline (51) and the corresponding dihydrothiazine (63) show a weaker activity.The biological profile of C 2696-Go has been investigated in detail.It appears to prevent implantation by its antiuterotropic activity and ability to inhibit desiduoma formation.