59997-96-5Relevant academic research and scientific papers
Exploiting sp2-Hybridisation in the Development of Potent 1,5-α-l-Arabinanase Inhibitors
Coyle, Travis,Debowski, Aleksandra W.,Varrot, Annabelle,Stubbs, Keith A.
, p. 974 - 978 (2017)
The synthesis of potent inhibitors of GH93 arabinanases as well as a synthesis of a chromogenic substrate to measure GH93 arabinanase activity are described. An insight into the reasons behind the potency of the inhibitors was gained through X-ray crystallographic analysis of the arabinanase Arb93A from Fusarium graminearum. These compounds lay a foundation for future inhibitor development as well as for the use of the chromogenic substrate in biochemical studies of GH93 arabinanases.
Synthesis of α-L-Araf and β-D-Galf series furanobiosides using mutants of a GH51 α-L-arabinofuranosidase
Zhao, Jiao,Esque, Jérémy,André, Isabelle,O'Donohue, Michael J.,Fauré, Régis
, (2021/09/06)
The GH-51 α-L-arabinofuranosidase from Thermobacillus xylanilyticus (TxAbf) possesses versatile catalytic properties, displaying not only the ability to hydrolyze glycosidic linkages but also to synthesize furanobiosides in α-L-Araf and β-D-Galf series. H
Enzymatic synthesis of oligo-d-galactofuranosides and l-arabinofuranosides: From molecular dynamics to immunological assays
Chlubnova, Ilona,Filipp, Dominik,Spiwok, Vojtech,Dvoakova, Hana,Daniellou, Richard,Nugier-Chauvin, Caroline,Kralova, Blanka,Ferrieres, Vincent
experimental part, p. 2092 - 2102 (2010/07/03)
D-Galactofuranosyl-containing conjugates are ubiquitous in many pathogenic microorganisms, but completely absent from mammals. As they may constitute interesting pharmacophores, recent works have been dedicated to their preparation. Besides well-reported
Synthesis of pentose-containing disahharides using a thermostable α-L-arabinofuranosidase
Remond, Caroline,Plantier-Royon, Richard,Aubry, Nathalie,Maes, Emmanuel,Bliard, Christophe,O'Donuhue, Michael J.
, p. 2018 - 2026 (2007/10/03)
To date, the enzymatically-catalysed synthesis of pentose-containing compounds has been limited to the production of oligo-β-(1->3)- and oligo-β-(1->4)-linked xylopyranosides. To our knowledge, no such syntheses have involved arabinofuranose or, indeed, a
